Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.
about
Cannabinoids as therapeutic agents in cancer: current status and future implicationsThe multiple cellular functions of the oncoprotein Golgi phosphoprotein 3Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXTSystemic therapy for selected skull base sarcomas: Chondrosarcoma, chordoma, giant cell tumour and solitary fibrous tumour/hemangiopericytoma.Genetic aberrations and molecular biology of skull base chordoma and chondrosarcoma.Comprehensive analysis of published studies involving systemic treatment for chondrosarcoma of bone between 2000 and 2013.Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling.HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas.Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma.Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone.BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors.Involvement of the soluble urokinase receptor in chondrosarcoma cell mobilization.Chondrosarcoma: with updates on molecular genetics.Mesenchymal stem cell transformation and sarcoma genesis.Curcumin binds in silico to anti-cancer drug target enzyme MMP-3 (human stromelysin-1) with affinity comparable to two known inhibitors of the enzyme.CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells.Mutant IDH is sufficient to initiate enchondromatosis in mice.Primary vascular tumors of bone: a spectrum of entities?The endocannabinoid system and cancer: therapeutic implication.Response of conventional chondrosarcoma to gemcitabine alone: a case reportPeriosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype.Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patientsPreclinical good laboratory practice-compliant safety study to evaluate biodistribution and tumorigenicity of a cartilage advanced therapy medicinal product (ATMP).FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.Peripheral chondrosarcoma progression is associated with increased type X collagen and vascularisation.Putative multifunctional signature of lung metastases in dedifferentiated chondrosarcoma.Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo.No preclinical rationale for IGF1R directed therapy in chondrosarcoma of boneTargeting the apoptotic pathway in chondrosarcoma using recombinant human Apo2L/TRAIL (dulanermin), a dual proapoptotic receptor (DR4/DR5) agonist.Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathwayLoss of β-catenin induces multifocal periosteal chondroma-like masses in miceNFAT restricts osteochondroma formation from entheseal progenitorsThe role of mesenchymal stem/progenitor cells in sarcoma: update and dispute.Ageing and the pathogenesis of osteoarthritis.Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.Interobserver reliability in the histopathological diagnosis of cartilaginous tumors in patients with multiple osteochondromasFrom an orphan disease to a generalized molecular mechanism: PTPN11 loss-of-function mutations in the pathogenesis of metachondromatosisLoss of pRB and p107 disrupts cartilage development and promotes enchondroma formation.Therapeutic molecular targets in human chondrosarcoma.Concise review: mesenchymal tumors: when stem cells go mad.
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Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Cartilage tumours and bone dev ...... possible therapeutic targets.
@en
Cartilage tumours and bone dev ...... possible therapeutic targets.
@nl
type
label
Cartilage tumours and bone dev ...... possible therapeutic targets.
@en
Cartilage tumours and bone dev ...... possible therapeutic targets.
@nl
prefLabel
Cartilage tumours and bone dev ...... possible therapeutic targets.
@en
Cartilage tumours and bone dev ...... possible therapeutic targets.
@nl
P356
P1476
Cartilage tumours and bone dev ...... d possible therapeutic targets
@en
P2093
Benjamin A Alman
Jay S Wunder
P2888
P304
P356
10.1038/NRC2869
P407
P577
2010-06-10T00:00:00Z