LATS tumor suppressor: a new governor of cellular homeostasis.
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Crosstalk between NDR kinase pathways coordinates cell cycle dependent actin rearrangementsThe MST/Hippo Pathway and Cell Death: A Non-Canonical AffairThe Regulatory Role of KIBRA and PTPN14 in Hippo Signaling and BeyondYAP-Mediated Mechanotransduction in Skeletal MuscleThe structure and function of NKAIN2-a candidate tumor suppressorRoles and mechanisms of cellular senescence in regulation of tissue homeostasisNEDD4: a promising target for cancer therapyProper actin ring formation and septum constriction requires coordinated regulation of SIN and MOR pathways through the germinal centre kinase MST-1Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiationEstablishment and mutation analysis of a novel malignant peritoneal mesothelioma cell line, TU-MM-1, using whole genome sequencing.Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines.Utilizing somatic mutation data from numerous studies for cancer research: proof of concept and applications.Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data.Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos.A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo.WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected]DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer17-AAG suppresses growth and invasion of lung adenocarcinoma cells via regulation of the LATS1/YAP pathway.Knockdown of yes-associated protein inhibits proliferation and downregulates large tumor suppressor 1 expression in MHCC97H human hepatocellular carcinoma cells.MicroRNA-135b regulates apoptosis and chemoresistance in colorectal cancer by targeting large tumor suppressor kinase 2.The roles of microRNAs and protein components of the microRNA pathway in lung development and diseases.Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming.LATS2 Positively Regulates Polycomb Repressive Complex 2.Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size.Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.Yes associated protein is a poor prognostic factor in well-differentiated lung adenocarcinomaMiR-93 enhances angiogenesis and metastasis by targeting LATS2.Decreased expression of LATS1 is correlated with the progression and prognosis of glioma.Micromanaging a large tumor suppressor.Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathwayThe LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulationCullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway.Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells.Loss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signalingThe Hippo pathway, p53 and cholesterolAJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol.Lats2 is critical for the pluripotency and proper differentiation of stem cells.The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer.
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LATS tumor suppressor: a new governor of cellular homeostasis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
LATS tumor suppressor: a new governor of cellular homeostasis.
@en
LATS tumor suppressor: a new governor of cellular homeostasis.
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type
label
LATS tumor suppressor: a new governor of cellular homeostasis.
@en
LATS tumor suppressor: a new governor of cellular homeostasis.
@nl
prefLabel
LATS tumor suppressor: a new governor of cellular homeostasis.
@en
LATS tumor suppressor: a new governor of cellular homeostasis.
@nl
P356
P1433
P1476
LATS tumor suppressor: a new governor of cellular homeostasis.
@en
P2093
Stacy Visser
Xiaolong Yang
P304
P356
10.4161/CC.9.19.13386
P577
2010-10-20T00:00:00Z