Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents.
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Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analoguesBicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase.New castanospermine glycoside analogues inhibit breast cancer cell proliferation and induce apoptosis without affecting normal cellsD(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independentIdentification of Novel Human Breast Carcinoma (MDA-MB-231) Cell Growth Modulators from a Carbohydrate-Based Diversity Oriented Synthesis Library.Recent developments in design and synthesis of bicyclic azasugars, carbasugars and related molecules as glycosidase inhibitors.The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience.sp2-Iminosugar O-, S-, and N-glycosides as conformational mimics of α-linked disaccharides; implications for glycosidase inhibition.Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against CancerGlycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases.Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.Neoadenoloside A, a highly functionalized diterpene C-glycoside, from Isodon adenolomus.Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.sp2 -Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathways.
P2860
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P2860
Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents.
@en
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents.
@nl
type
label
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents.
@en
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents.
@nl
prefLabel
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents.
@en
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents.
@nl
P2093
P50
P356
P1476
Synthesis of N-, S-, and C-gly ...... activity as antitumour agents
@en
P2093
Ahmed Ahidouch
Halima Ouadid-Ahidouch
Maud Chasseraud
Rocío Rísquez-Cuadro
P2860
P304
P356
10.1039/C0CC00446D
P407
P577
2010-06-15T00:00:00Z