Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists.
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ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and traumaPrevention by NMDA receptor antagonists of the centrally-evoked increases of cardiac inotropic responses in rabbitsTARP auxiliary subunits switch AMPA receptor antagonists into partial agonistsHeteromeric NMDA receptors: molecular and functional distinction of subtypesGene structure of the murine N-methyl D-aspartate receptor subunit NR2CAgonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cellsCharacterization of ionotropic glutamate receptors in human lymphocytesIPF, a vesicular uptake inhibitory protein factor, can reduce the Ca(2+)-dependent, evoked release of glutamate, GABA and serotonin.Neurologic effects of alcoholismOverexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: application of a novel protein folding screen.Efficient, complete deletion of synaptic proteins using CRISPR.Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid.Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb.Subunit arrangement and function in NMDA receptors.Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1.CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activityD-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptorsExcitatory amino acids contribute to the pathogenesis of perinatal hypoxic-ischemic brain injury.Purification, reconstitution, and cloning of an NMDA receptor-ion channel complex from rat brain synaptic membranes: implications for neurobiological changes in alcoholism.Response Properties of a Newly Identified Tristratified Narrow Field Amacrine Cell in the Mouse RetinaAMPA receptor regulation mechanisms: future target for safer neuroprotective drugs.Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.Effects of acromelic acid A on the binding of [3H]-kainic acid and [3H]-AMPA to rat brain synaptic plasma membranes.Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture.Signal transmission in the parallel fiber-Purkinje cell system visualized by high-resolution imaging.Stable expression of a functional GluR6 homomeric glutamate receptor channel in mammalian cells.Inhibition of NMDA-type glutamate receptors induces arousal from torpor in hibernating arctic ground squirrels (Urocitellus parryii).Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.Effect of latent iron deficiency on GABA and glutamate neuroreceptors in rat brain.Excitatory amino acid receptor-stimulated phosphoinositide turnover in primary cerebrocortical cultures.Ionotropic glutamate receptor types leading to adenosine-mediated inhibition of electrically evoked [3H]-noradrenaline release in rabbit brain cortex slices.Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated.Carboxylic acid (bio)isosteres in drug design.Total syntheses of (-)-alpha-kainic acid and (+)-alpha-allokainic acid via stereoselective C-H insertion and efficient 3,4-stereocontrolPurified unitary kainate/alpha-amino-3-hydroxy-5-methylisooxazole-propionate (AMPA) and kainate/AMPA/N-methyl-D-aspartate receptors with interchangeable subunitsAlternative splicing generates functionally distinct N-methyl-D-aspartate receptors.Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous systemRapid activation of hippocampal casein kinase II during long-term potentiationRecent advances in the physiology and pharmacology of pain: plasticity and its implications for clinical analgesia.Smithkline Beecham Prize for Young Psychopharmacologists: A review of the relationship between calcium channels and psychiatric disorders.
P2860
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P2860
Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Structure-activity relationshi ...... s and competitive antagonists.
@en
Structure-activity relationshi ...... s and competitive antagonists.
@nl
type
label
Structure-activity relationshi ...... s and competitive antagonists.
@en
Structure-activity relationshi ...... s and competitive antagonists.
@nl
prefLabel
Structure-activity relationshi ...... s and competitive antagonists.
@en
Structure-activity relationshi ...... s and competitive antagonists.
@nl
P2093
P1476
Structure-activity relationshi ...... s and competitive antagonists.
@en
P2093
Krogsgaard-Larsen P
Watkins JC
P356
10.1016/0165-6147(90)90038-A
P577
1990-01-01T00:00:00Z