Structure, function, and mechanism of progranulin; the brain and beyond. - Wikidata - awgldk - TriplyDB

Structure, function, and mechanism of progranulin; the brain and beyond.

Structure, function, and mechanism of progranulin; the brain and beyond.

http://www.wikidata.org/entity/Q37892442

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Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders The role of progranulin in diabetes and kidney disease TDP-43: a new player on the AD field?Mechanisms of granulin deficiency: lessons from cellular and animal models Progranulin: at the interface of neurodegenerative and metabolic diseases Expression of the growth factor progranulin in endothelial cells influences growth and development of blood vessels: a novel mouse model Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency The Evolution of the Secreted Regulatory Protein Progranulin Multimodal FMRI resting-state functional connectivity in granulin mutations: the case of fronto-parietal dementia.The epigenetic dimension of Alzheimer's disease: causal, consequence, or curiosity?Granulin exacerbates lupus nephritis via enhancing macrophage M2b polarization.Progranulin is a novel independent predictor of disease progression and overall survival in chronic lymphocytic leukemia.Low plasma progranulin levels in children with autism.Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.Serum and Urinary Progranulin in Diabetic Kidney Disease.Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection.Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.EphA2 is a functional receptor for the growth factor progranulin.Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.The Role of PGRN in Alzheimer's Disease.The lysosomal protein cathepsin L is a progranulin protease.The Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels.Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy.Progranulin shows cytoprotective effects on trophoblast cells in vitro but does not antagonize TNF-α-induced apoptosis.Molecular Genetics of Neurodegenerative Dementias.Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.Validation of reference genes for quantitative real-time PCR in valproic acid rat models of autism.Progranulin Protein Levels in Cerebrospinal Fluid in Primary Neurodegenerative Dementias.Progranulin Plays a Central Role in Host Defense during Sepsis by Promoting Macrophage Recruitment.The CNGRC-GG-D(KLAKLAK)2 peptide induces a caspase-independent, Ca2+-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13 Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease.Progranulin and the receptor tyrosine kinase EphA2, partners in crime?Sex differences in the prevalence of genetic mutations in FTD and ALS: A meta-analysis.Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4⁺ Foxp3⁺ regulatory T cells.Progranulin does not inhibit TNF and lymphotoxin-α signalling through TNF receptor 1.Proinflammatory progranulin antibodies in inflammatory bowel diseases.Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.Progranulin and its biological effects in cancer.

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Structure, function, and mechanism of progranulin; the brain and beyond.

http://www.wikidata.org/entity/Q37892442

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 21 June 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Structure, function, and mechanism of progranulin; the brain and beyond.

@en

Structure, function, and mechanism of progranulin; the brain and beyond.

@nl

type

label

Structure, function, and mechanism of progranulin; the brain and beyond.

@en

Structure, function, and mechanism of progranulin; the brain and beyond.

@nl

prefLabel

Structure, function, and mechanism of progranulin; the brain and beyond.

@en

Structure, function, and mechanism of progranulin; the brain and beyond.

@nl

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S12031-011-9569-4

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Journal of Molecular Neuroscience

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Structure, function, and mechanism of progranulin; the brain and beyond.

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Andrew Bateman

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Babykumari P Chitramuthu

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Hugh P J Bennett

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Huishi Toh

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P2860

Chronic traumatic encephalopathy: a potential late effect of sport-related concussive and subconcussive head trauma

Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains

Sortilin is essential for proNGF-induced neuronal cell death

Structural and functional analysis of a promoter of the human granulin/epithelin gene

The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription

Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor)

The zebrafish progranulin gene family and antisense transcripts.

Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Creation of human tumour cells with defined genetic elements

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s12031-011-9569-4

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10.1007/S12031-011-9569-4

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3

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45

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2011-06-21T00:00:00Z

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21691802

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