Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
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Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?Design Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone PulsesMutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in miceImproving the physiological realism of experimental models.Model for glucagon secretion by pancreatic α-cells.A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells.Genetic targeting of a small fluorescent zinc indicator to cell surface for monitoring zinc secretion.Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activationMinireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes.Dynamic monitoring of glucagon secretion from living cells on a microfluidic chip.Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress responseA novel insulinotropic mechanism of whole grain-derived γ-oryzanol via the suppression of local dopamine D2 receptor signalling in mouse isletEphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells.A computational systems analysis of factors regulating α cell glucagon secretion.Regulation of glucagon secretion in normal and diabetic human islets by γ-hydroxybutyrate and glycine.HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.UCP2 regulates the glucagon response to fasting and starvationTolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells.Paracrine regulation of glucagon secretion: the β/α/δ model.Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cellsOver-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia.High-fat diet consumption during pregnancy and the early post-natal period leads to decreased α cell plasticity in the nonhuman primateDiminished adenosine A1 receptor expression in pancreatic α-cells may contribute to the pathology of type 1 diabetes.Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.Modeling the pancreatic α-cell: dual mechanisms of glucose suppression of glucagon secretion.Regulation of calcium in pancreatic α- and β-cells in health and disease.Ghrelin, the proglucagon-derived peptides and peptide YY in nutrient homeostasis.Principles of endocrinology.K(ATP) channels and islet hormone secretion: new insights and controversies.The role of glucagon on type 2 diabetes at a glance.Neural regulation of pancreatic islet cell mass and function.Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls β, α, and δ-cell masses in genetic obese mice.Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretionGlucose control of glucagon secretion-'There's a brand-new gimmick every year'.Glucose-dependent downregulation of glucagon gene expression mediated by selective interactions between ALX3 and PAX6 in mouse alpha cells.Role of histamine H3 receptor in glucagon-secreting αTC1.6 cellsDelta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin.Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls.
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P2860
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
@en
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
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type
label
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
@en
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
@nl
prefLabel
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
@en
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
@nl
P2093
P2860
P1476
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
@en
P2093
J N Walker
P R V Johnson
R Ramracheya
P2860
P304
P356
10.1111/J.1463-1326.2011.01450.X
P478
13 Suppl 1
P577
2011-10-01T00:00:00Z