Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis.
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ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationFunctional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosisTDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegansRegulation of CuZnSOD and its redox signaling potential: implications for amyotrophic lateral sclerosisAnalysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2.Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the MutationGolgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences.Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis.Mutations in BICD2, which encodes a golgin and important motor adaptor, cause congenital autosomal-dominant spinal muscular atrophySelective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9.Enhanced uncoupling of the mitochondrial respiratory chain as a potential source for amyotrophic lateral sclerosisActivation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis.An enhanced integrated stress response ameliorates mutant SOD1-induced ALS.Protein misdirection inside and outside motor neurons in Amyotrophic Lateral Sclerosis (ALS): a possible clue for therapeutic strategiesER Dysfunction and Protein Folding Stress in ALS.The role of s-nitrosylation and s-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration.Protein misfolding, amyotrophic lateral sclerosis and guanabenz: protocol for a phase II RCT with futility design (ProMISe trial).TFG-Related Neurologic Disorders: New Insights Into Relationships Between Endoplasmic Reticulum and Neurodegeneration.Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis.Addition of exogenous SOD1 aggregates causes TDP-43 mislocalisation and aggregation.Crosstalk between Endoplasmic Reticulum Stress and Protein Misfolding in Neurodegenerative Diseases
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P2860
Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Stress signaling from the endo ...... amyotrophic lateral sclerosis.
@en
Stress signaling from the endo ...... amyotrophic lateral sclerosis.
@nl
type
label
Stress signaling from the endo ...... amyotrophic lateral sclerosis.
@en
Stress signaling from the endo ...... amyotrophic lateral sclerosis.
@nl
prefLabel
Stress signaling from the endo ...... amyotrophic lateral sclerosis.
@en
Stress signaling from the endo ...... amyotrophic lateral sclerosis.
@nl
P2860
P921
P356
P1433
P1476
Stress signaling from the endo ...... amyotrophic lateral sclerosis
@en
P2093
Julie D Atkin
P2860
P304
P356
10.1002/IUB.520
P577
2011-08-10T00:00:00Z