Molecular scaffolds using multiple orthogonal conjugations: applications in chemical biology and drug discovery.
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Adapter reagents for protein site specific dye labelingA combinatorial approach toward smart libraries of discontinuous epitopes of HIV gp120 on a TAC synthetic scaffold.Click chemistry patents and their impact on drug discovery and chemical biology.Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.Novel Strategy for Preparing Dual-Modality Optical/PET Imaging Probes via Photo-Click Chemistry.Inverse electron demand Diels-Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme.Patchwork protein chemistry: a practitioner's treatise on the advances in synthetic peptide stitchery.Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs.Understanding and applying tyrosine biochemical diversity."Click" reactions: a versatile toolbox for the synthesis of peptide-conjugates."AND" luminescent "reactive" molecular logic gates: a gateway to multi-analyte bioimaging and biosensing.Emerging trends in enzyme inhibition by multivalent nanoconstructs.Azo-Based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges.Bioorthogonal Chemistry-Introduction and Overview.Dual modification of biomolecules.Strained cyclooctyne as a molecular platform for construction of multimodal imaging probes.Click-chemistry approaches to π-conjugated polymers for organic electronics applications.Synthesis, characterization and DNA interaction studies of new triptycene derivatives.Cyclopentane-peptide nucleic acids for qualitative, quantitative, and repetitive detection of nucleic acids.Nanoparticles under the light: click functionalization by photochemical thiol-yne reaction, towards double click functionalization.NIR mega-Stokes fluorophores for bioorthogonal labeling and energy transfer systems--an efficient quencher for daunomycin.A coumarin derivative as a fluorogenic glycoproteomic probe for biological imaging.Fluorogenic Behaviour of the Hetero-Diels-Alder Ligation of 5-Alkoxyoxazoles with Maleimides and their Applications.Multicomponent Aqueous Synthesis of Iodo-1,2,3-triazoles: Single-Step Models for Dual Modification of Free Peptide and Radioactive Iodo Labeling.Biomolecular assemblies combining two orthogonal copper-mediated ligations in a one-pot reaction.A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds.The molecular basis of conjugated polyyne biosynthesis in phytopathogenic bacteria.The first peripherally masked thiol dendrimers: a facile and highly efficient functionalization strategy of polyester dendrimers via one-pot xanthate deprotection/thiol-acrylate Michael addition reactions.A trifunctional linker suitable for conducting three orthogonal click chemistries in one pot.Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs.Protecting-group-free synthesis of chain-end multifunctional polymers by combining ATRP with thiol–epoxy ‘click’ chemistryKinetic comparison of 13 homogeneous thiol–X reactionsSynthesis of Carbohydrate-Functionalised Sequence-Defined Oligo(amidoamine)s by Photochemical ThiolEne Coupling in a Continuous Flow ReactorTarget validation using in-cell small molecule clickable imaging probes
P2860
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P2860
Molecular scaffolds using multiple orthogonal conjugations: applications in chemical biology and drug discovery.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Molecular scaffolds using mult ...... al biology and drug discovery.
@en
type
label
Molecular scaffolds using mult ...... al biology and drug discovery.
@en
prefLabel
Molecular scaffolds using mult ...... al biology and drug discovery.
@en
P2860
P356
P1476
Molecular scaffolds using mult ...... al biology and drug discovery.
@en
P2860
P304
P356
10.1002/ANIE.201200002
P407
P577
2012-04-19T00:00:00Z