What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders.
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Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseTargeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromesAlzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss.Soy-based diet exacerbates seizures in mouse models of neurological diseaseNeuronal nucleus and cytoplasm volume deficit in children with autism and volume increase in adolescents and adults.Fragile X mental retardation protein: from autism to neurodegenerative disease.Integrative network analysis unveils convergent molecular pathways in Parkinson's disease and diabetes.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.Beta-amyloid peptides undergo regulated co-secretion with neuropeptide and catecholamine neurotransmitters.APP Causes Hyperexcitability in Fragile X Mice.Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.Anti-amyloid beta to tau - based immunization: Developments in immunotherapy for Alzheimer disease.DISC1 regulates trafficking and processing of APP and Aβ generation.Increased Extra-axial Cerebrospinal Fluid in High-Risk Infants Who Later Develop Autism.MiR-144-3p and Its Target Gene β-Amyloid Precursor Protein Regulate 1-Methyl-4-Phenyl-1,2-3,6-Tetrahydropyridine-Induced Mitochondrial Dysfunction.Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism.Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation.Developing BACE-1 inhibitors for FXS.Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission.Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.Seeds of neuroendocrine doubt.
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P2860
What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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What's hAPPening at synapses? ...... oid in neurological disorders.
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type
label
What's hAPPening at synapses? ...... oid in neurological disorders.
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prefLabel
What's hAPPening at synapses? ...... oid in neurological disorders.
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P2860
P356
P1433
P1476
What's hAPPening at synapses? ...... oid in neurological disorders.
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P2093
C J Westmark
P2860
P2888
P304
P356
10.1038/MP.2012.122
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P577
2012-08-28T00:00:00Z