A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned.
about
Large scale characterization of the LC13 TCR and HLA-B8 structural landscape in reaction to 172 altered peptide ligands: a molecular dynamics simulation studyEffective T helper cell responses against retroviruses: are all clonotypes equal?Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I MoleculeT-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex InteractionsStructure of the Chicken CD3 / Heterodimer and Its Assembly with the T Cell ReceptorMolecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell RepertoireMolecular Basis of a Dominant T Cell Response to an HIV Reverse Transcriptase 8-mer Epitope Presented by the Protective Allele HLA-B*51:01Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell EpitopesEffect of CDR3 Sequences and Distal V Gene Residues in Regulating TCR-MHC Contacts and Ligand SpecificityA molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cellsRecognition of vitamin B metabolites by mucosal-associated invariant T cellsT-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac diseaseT cell receptor reversed polarity recognition of a self-antigen major histocompatibility complexTCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoireClonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.Advances in the study of HLA-restricted epitope vaccines.The molecular bases of δ/αβ T cell-mediated antigen recognition.The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitopeElevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumorsImmunogenicity of infectious pathogens and vaccine antigens.Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia MoleculesStructure-Based, Rational Design of T Cell Receptors.T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.Increased diversity of the HLA-B40 ligandome by the presentation of peptides phosphorylated at their main anchor residueThe versatility of the αβ T-cell antigen receptor.Duality of the murine CD8 compartment.Endogenous-peptide-dependent alloreactivity: new scientific insights and clinical implications.The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination.Understanding the complexity and malleability of T-cell recognition.Current status and future challenges in T-cell receptor/peptide/MHC molecular dynamics simulations.Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens.Insights into immune structure, recognition, and signaling.Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope.Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire.Immune parameters to consider when choosing T-cell receptors for therapy.Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy.A study of CDR3 loop dynamics reveals distinct mechanisms of peptide recognition by T-cell receptors exhibiting different levels of cross-reactivity.Computational characterization of residue couplings and micropolymorphism-induced changes in the dynamics of two differentially disease-associated human MHC class-I alleles.Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
P2860
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P2860
A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
A structural voyage toward an ...... earned and much to be learned.
@en
type
label
A structural voyage toward an ...... earned and much to be learned.
@en
prefLabel
A structural voyage toward an ...... earned and much to be learned.
@en
P2860
P50
P1476
A structural voyage toward an ...... earned and much to be learned.
@en
P2860
P356
10.1111/J.1600-065X.2012.01159.X
P577
2012-11-01T00:00:00Z