The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
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EAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300Targeted Therapies in Adult B-Cell MalignanciesTargeting DNA damage response in cancer therapyA synthetic manassantin a derivative inhibits hypoxia-inducible factor 1 and tumor growthProbing hypoxia-induced staurosporine resistance in prostate cancer cells with a microfluidic culture system.Beclin-1-independent autophagy positively regulates internal ribosomal entry site-dependent translation of hypoxia-inducible factor 1α under nutrient deprivation.Peritoneal milky spots serve as a hypoxic niche and favor gastric cancer stem/progenitor cell peritoneal dissemination through hypoxia-inducible factor 1α.The return of metabolism: biochemistry and physiology of the pentose phosphate pathwayInhibition of vascular endothelial growth factor A and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculatureThe In Vitro and In Vivo Activity of the Microtubule Disruptor STX140 Is Mediated by Hif-1 Alpha and CAIX ExpressionIDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma.Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.HIF-1α regulates EMT via the Snail and β-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis.Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis.Nuclear translocation of HIF-1α induced by influenza A (H1N1) infection is critical to the production of proinflammatory cytokinesAMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms.Influence of different hypoxia models on metastatic potential of SGC-7901 gastric cancer cells.Application of two-dimensional gel-based mass spectrometry to functionally dissect resistance to targeted cancer therapy.Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1α in HCA-7 human colon cancer cells.Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer.Tumor heterogeneity, clonal evolution, and therapy resistance: an opportunity for multitargeting therapy.HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma.Chronodisruption increases cardiovascular risk in zebrafish via reduced clearance of senescent erythrocytes.Hypoxia enhances the radioresistance of mouse mesenchymal stromal cells.The Transcription Factor Hif-1 Enhances the Radio-Resistance of Mouse MSCs.Hypoxia reduces and redirects selenoprotein biosynthesisCellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region
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The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
@en
type
label
The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
@en
prefLabel
The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
@en
P2860
P356
P1433
P1476
The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2012.510
P407
P577
2012-11-19T00:00:00Z
P6179
1033580014