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Ubiquitin signaling in immune responsesLinear ubiquitination in immunityPellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination.Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages.RIP kinases: key decision makers in cell death and innate immunity.Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO.EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice.Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.A quantitative genome-wide RNAi screen in C. elegans for antifungal innate immunity genes.The Arabidopsis Protein Phosphatase PP2C38 Negatively Regulates the Central Immune Kinase BIK1.Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia.Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity.E3 ubiquitin ligases Pellinos as regulators of pattern recognition receptor signaling and immune responses.Role of E3 ubiquitin ligases in insulin resistance.Molecular mechanisms of regulation of Toll-like receptor signalingDeficiency in IRAK4 activity attenuates manifestations of murine Lupus.Endotoxin Tolerance Inhibits Degradation of Tumor Necrosis Factor Receptor-Associated Factor 3 by Suppressing Pellino 1 Expression and the K48 Ubiquitin Ligase Activity of Cellular Inhibitor of Apoptosis Protein 2.The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities.The TGFβ-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration.The family of the interleukin-1 receptors.Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.Apigenin-7-O-β-D-glucuronide inhibits LPS-induced inflammation through the inactivation of AP-1 and MAPK signaling pathways in RAW 264.7 macrophages and protects mice against endotoxin shock.Proteomic Analysis of Neuroblastoma-Derived Exosomes: New Insights into a Metastatic Signature.Peli1 modulates the subcellular localization and activity of Mdmx.A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors.Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation.Casein kinase 1α: biological mechanisms and theranostic potential.The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome.
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The roles of Pellino E3 ubiquitin ligases in immunity.
@en
type
label
The roles of Pellino E3 ubiquitin ligases in immunity.
@en
prefLabel
The roles of Pellino E3 ubiquitin ligases in immunity.
@en
P2860
P356
P1476
The roles of Pellino E3 ubiquitin ligases in immunity.
@en
P2860
P304
P356
10.1038/NRI3599
P577
2014-01-21T00:00:00Z