Receptor tyrosine kinases: legacy of the first two decades
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Toxicological assessment of CoO and La2O3 metal oxide nanoparticles in human small airway epithelial cellsTOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-JunUnderstanding the Interplay between Expression, Mutation and Activity of ALK Receptor in Rhabdomyosarcoma Cells for Clinical Application of Small-Molecule InhibitorsSpatially defined EGF receptor activation reveals an F-actin-dependent phospho-Erk signaling complex.In silico discovery of potential VEGFR-2 inhibitors from natural derivatives for anti-angiogenesis therapy.Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).Essential roles of Gab1 tyrosine phosphorylation in growth factor-mediated signaling and angiogenesisTherapeutic control and resistance of the EGFR-driven signaling network in glioblastoma.Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors.Constitutive asymmetric dimerization drives oncogenic activation of epidermal growth factor receptor carboxyl-terminal deletion mutants.Identification and classification of small molecule kinases: insights into substrate recognition and specificity.Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon RegenerationErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs).One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopyAdopting ALK and LTK.Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactionsEph receptor signaling and ephrinsThe EGFR family: not so prototypical receptor tyrosine kinases.Signal, transduction, and the hematopoietic stem cell.Diverse Molecular Targets for Chalcones with Varied Bioactivities.The untapped potential of tyrosine-based G protein signaling.Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.Acquired Resistance to Clinical Cancer Therapy: A Twist in Physiological Signaling.The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer.Epigenetic regulation of RTK signaling.NF-κB as the main node of resistance to receptor tyrosine kinase inhibitors in triple-negative breast cancer.Evolution of the EGFR pathway in Metazoa and its diversification in the planarian Schmidtea mediterranea.A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors.A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo.Dimerization of the EphA1 receptor tyrosine kinase transmembrane domain: Insights into the mechanism of receptor activation.Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation.Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody.Whole Genome Duplications Shaped the Receptor Tyrosine Kinase Repertoire of Jawed Vertebrates.G protein coupled growth factor receptor tyrosine kinase: no longer an oxymoron.MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation.Emerging functions of the EGFR in cancer.SPC24 promotes osteosarcoma progression by increasing EGFR/MAPK signaling.Quantifying the Interaction between EGFR Dimers and Grb2 in Live Cells.
P2860
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P2860
Receptor tyrosine kinases: legacy of the first two decades
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Receptor tyrosine kinases: legacy of the first two decades
@en
type
label
Receptor tyrosine kinases: legacy of the first two decades
@en
prefLabel
Receptor tyrosine kinases: legacy of the first two decades
@en
P2860
P1476
Receptor tyrosine kinases: legacy of the first two decades
@en
P2860
P356
10.1101/CSHPERSPECT.A008912
P577
2014-03-01T00:00:00Z