Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer cores.
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ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancerCore Binding Factor Acute Myeloid Leukemia: New Prognostic Categories and Therapeutic OpportunitiesLong terminal repeat regions from exogenous but not endogenous feline leukemia viruses transactivate cellular gene expression.Core-binding factor influences the disease specificity of Moloney murine leukemia virusIncreased induction of osteopetrosis, but unaltered lymphomagenicity, by murine leukemia virus SL3-3 after mutation of a nuclear factor 1 site in the enhancerType B leukemogenic virus has a T-cell-specific enhancer that binds AML-1.SARS coronavirus 3b accessory protein modulates transcriptional activity of RUNX1b.Duplication of U3 sequences in the long terminal repeat of mink cell focus-inducing viruses generates redundancies of transcription factor binding sites important for the induction of thymomasIncreased lymphomagenicity and restored disease specificity of AML1 site (core) mutant SL3-3 murine leukemia virus by a second-site enhancer variant evolved in vivo.Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoterThe feline leukemia virus long terminal repeat contains a potent genetic determinant of T-cell lymphomagenicityAn SL3-3 murine leukemia virus enhancer variant more pathogenic than the wild type obtained by assisted molecular evolution in vivoThe extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesisMutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns.Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells.Cytoplasmic sequestration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor alpha (CBFalpha) subunit by the leukemia-related PEBP2/CBFbeta-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation.Selection of reversions and suppressors of a mutation in the CBF binding site of a lymphomagenic retrovirusSuppressor mutations within the core binding factor (CBF/AML1) binding site of a T-cell lymphomagenic retrovirus.ETS-core binding factor: a common composite motif in antigen receptor gene enhancers.CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.B-Cell lymphoma induction by akv murine leukemia viruses harboring one or both copies of the tandem repeat in the U3 enhancer.Transcriptional activation of a retrovirus enhancer by CBF (AML1) requires a second factor: evidence for cooperativity with c-Myb.Second-site proviral enhancer alterations in lymphomas induced by enhancer mutants of SL3-3 murine leukemia virus: negative effect of nuclear factor 1 binding site.Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.The potent enhancer activity of the polycythemic strain of spleen focus-forming virus in hematopoietic cells is governed by a binding site for Sp1 in the upstream control region and by a unique enhancer core motif, creating an exclusive target for PCompetitive binding of viral E2 protein and mammalian core-binding factor to transcriptional control sequences of human papillomavirus type 8 and bovine papillomavirus type 1.RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors.Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.
P2860
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P2860
Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer cores.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Transcriptional activity of co ...... leukemia virus enhancer cores.
@en
type
label
Transcriptional activity of co ...... leukemia virus enhancer cores.
@en
prefLabel
Transcriptional activity of co ...... leukemia virus enhancer cores.
@en
P2093
P2860
P1433
P1476
Transcriptional activity of co ...... leukemia virus enhancer cores.
@en
P2093
P2860
P304
P407
P577
1995-05-01T00:00:00Z