Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter
about
The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cellsThe MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion proteinModulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9Association of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn's disease: a case-control studyPolymerization of the SAM domain of TEL in leukemogenesis and transcriptional repressionAML1 interconnected pathways of leukemogenesisSUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivoRegulation of Ets function by protein - protein interactions.Ets target genes: past, present and future.Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein.TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1.Proteins of the ETS family with transcriptional repressor activity.Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia.The Runx genes: lineage-specific oncogenes and tumor suppressors.Identification of transcripts modulated by ETV6 expression.Revealing the role of TEL/AML1 for leukemic cell survival by RNAi-mediated silencing.Mechanism of ETV6-RUNX1 Leukemia.The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods.The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation.Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.Optimization of proximity ligation assay (PLA) for detection of protein interactions and fusion proteins in non-adherent cells: application to pre-B lymphocytes.Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter.ETV6/RUNX1 induces reactive oxygen species and drives the accumulation of DNA damage in B cells.RUNX1-RUNX1 homodimerization modulates RUNX1 activity and function.Molecular processes involved in B cell acute lymphoblastic leukaemia.MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice.TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases.FLT3 is fused to ETV6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13)(p13;q12) translocation.
P2860
Q24294810-C89100F0-AA4F-4091-9681-AB23D1B5753FQ24300030-208F893F-9564-4361-A843-21491730B137Q24522515-6EC8214A-69DD-4DA3-AD33-ADC48EB8963FQ24648208-D0D8C026-6FBE-4731-9165-2ABD59599039Q24794971-CB376F8F-C844-451E-8FA5-D7D070575179Q27633822-22B4A1F7-7DD3-472A-9983-2EB516DDFBB8Q28184349-51FCC803-72AF-487F-BA4D-703BCEA781A8Q28201653-CA08F8A6-BCA1-4664-8A74-DFC0B16591C9Q33933221-464992D4-251F-4A62-B22C-867BDCDB87C9Q33933227-D0A63A88-7761-49A2-9767-A00DD67AFBB0Q33959609-14854DB4-F62A-45F9-9D76-A0C446AF999DQ33964993-698520E2-9B85-4367-9207-F9DD730394BFQ34139422-52B4CACC-4796-4245-8433-66DCB6E38902Q35779725-68204842-0AAF-43FB-9CC7-C2DEB711A3B9Q35779743-F751D446-371E-42C5-8D49-3038F203A79EQ38308120-CEC3B389-61EC-4669-B663-7769C3CD5F6FQ38339066-08E2327B-B7DE-47A0-AB2F-B76FD527DAFEQ38744459-19EFB566-76F1-4BF5-89FA-6EF10C006C47Q39079942-4B089982-8055-407F-9197-08B3F8660317Q39631307-11B64B10-4D75-404F-94DA-F3BD76BFF6DAQ40937444-6B3C8BC4-8BCE-4C81-9456-F17F4FA9DFD2Q41079720-921C9ED6-0C29-407C-9E89-15AB76E54388Q41634601-6CB72DAB-F716-4326-87C4-45EAB3E0D921Q42468049-1258B1FB-C204-4BB5-A81E-EC0A674A0AFCQ42821539-9CFC6C73-4D56-4AD3-AE55-5D68929255B1Q42830201-011E1764-F89E-4729-9ED0-61A75C5B87B2Q48218289-83807406-B7CE-4EE7-93CB-D788B07CF4F0Q53344487-00398A5D-7EF7-4A41-8F4E-5BA95D2FAF01Q54397331-C3447FEC-D024-48F8-8CBA-31217ECC743AQ54597920-C0D23944-5A8F-4DB0-811E-6863DB442720
P2860
Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Functional characterization of ...... of the MCSFR proximal promoter
@ast
Functional characterization of ...... of the MCSFR proximal promoter
@en
type
label
Functional characterization of ...... of the MCSFR proximal promoter
@ast
Functional characterization of ...... of the MCSFR proximal promoter
@en
prefLabel
Functional characterization of ...... of the MCSFR proximal promoter
@ast
Functional characterization of ...... of the MCSFR proximal promoter
@en
P2093
P2860
P356
P1476
Functional characterization of ...... of the MCSFR proximal promoter
@en
P2093
C Hetherington
G Nucifora
J D Rowley
Y Ben-David
P2860
P304
P356
10.1073/PNAS.94.5.1949
P407
P577
1997-03-01T00:00:00Z