Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.
about
Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferationThe quantal theory of how the immune system discriminates between "self and non-self"Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activationp70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytesIntegrating signals from the T-cell receptor and the interleukin-2 receptorTyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteinsNegative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity.The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexesSTAT signaling in the pathogenesis and treatment of cancerStaphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins)Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cellsThe significance of tetramerization in promoter recruitment by Stat5.IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cellsSignaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activityActivation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.Inhibition of response to alpha interferon by Mycobacterium tuberculosis.Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter.Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cellsProtein kinase D. A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytesInhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion.Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene.Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha geneAnticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.Global intron retention mediated gene regulation during CD4+ T cell activation.Following the cytokine signaling pathway to leukemogenesis: a chronologyNuclear Phosphoproteomic Screen Uncovers ACLY as Mediator of IL-2-induced Proliferation of CD4+ T lymphocytes.Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome.Thrombopoietin activates a STAT5-like factor in hematopoietic cells.STAT heterodimers in immunity: A mixed message or a unique signal?Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.STAT3 Expression in Host Myeloid Cells Controls Graft-versus-Host Disease Severity.STAT5 and CD4 + T Cell Immunity.Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversityLY294002 and rapamycin co-operate to inhibit T-cell proliferation.Selective Inhibition of Janus Kinase 3 Has No Impact on Infarct Size or Neurobehavioral Outcomes in Permanent Ischemic Stroke in MiceConditional IL-2 Gene Deletion: Consequences for T Cell Proliferation.Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells.
P2860
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P2860
Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Activation of JAK kinases and ...... eptor, in human T lymphocytes.
@en
type
label
Activation of JAK kinases and ...... eptor, in human T lymphocytes.
@en
prefLabel
Activation of JAK kinases and ...... eptor, in human T lymphocytes.
@en
P2093
P2860
P1433
P1476
Activation of JAK kinases and ...... ceptor, in human T lymphocytes
@en
P2093
A Ziemiecki
B A Witthuhn
C Beadling
D A Cantrell
P2860
P304
P356
10.1002/J.1460-2075.1994.TB06898.X
P407
P577
1994-12-01T00:00:00Z