Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.
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STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylationJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytesDNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sitesRequirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cellsStat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformationMapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization.Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases.Galanin regulates prolactin release and lactotroph proliferation.Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha geneControl of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway.Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptorEpstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways.STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoAEpstein-Barr virus regulates STAT1 through latent membrane protein 1.Interleukin-13 induction of 15-lipoxygenase gene expression requires p38 mitogen-activated protein kinase-mediated serine 727 phosphorylation of Stat1 and Stat3.The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation.Comparison of the transactivation domains of Stat5 and Stat6 in lymphoid cells and mammary epithelial cells.Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase.Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription.Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation.Expression of v-src in mammary epithelial cells induces transcription via STAT3Conditional IL-2 Gene Deletion: Consequences for T Cell Proliferation.Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks.
P2860
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P2860
Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Interleukin-2 activation of ST ...... Raf1/ERK2 MAP kinase pathway.
@en
type
label
Interleukin-2 activation of ST ...... Raf1/ERK2 MAP kinase pathway.
@en
prefLabel
Interleukin-2 activation of ST ...... Raf1/ERK2 MAP kinase pathway.
@en
P2093
P2860
P1433
P1476
Interleukin-2 activation of ST ...... e Raf1/ERK2 MAP kinase pathway
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1996.TB00541.X
P407
P577
1996-04-01T00:00:00Z