The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.
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Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factorRepression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP betaInterleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cellsA functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptorSignaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha componentChoice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptorsFunctional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3Growth hormone inhibits rat liver alpha-1-acid glycoprotein gene expression in vivo and in vitroDecreased expression levels of rat liver glutathione S-transferase A2 and albumin during the acute phase response are mediated by HNF1 (hepatic nuclear factor 1) and IL6DEX-NPDisruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulationDifferential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activationMesangial cell gelatinase A synthesis is attenuated by oscillating hyperbaric pressureManipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens.Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.ATX-LPA receptor axis in inflammation and cancer.MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.STAT protein complexes activated by interferon-gamma and gp130 signaling molecules differ in their sequence preferences and transcriptional induction properties.Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of JActivation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gammaSignal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes.Genomic dissection of the cytokine-controlled STAT5 signaling network in liverIsolation and characterization of the human gp130 promoter. Regulation by STATS.Interleukin-6 and JAK2/STAT3 signaling mediate the reversion of dexamethasone resistance after dexamethasone withdrawal in 7TD1 multiple myeloma cellsActivation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.STAT3 regulation of glioblastoma pathogenesis.The JAK-STAT pathway at twenty.Characterization of the IL-6 responsive elements in the gamma fibrinogen gene promoter.Mechanism of negative regulation of rat glutathione S-transferase A2 by the cytokine interleukin 6Computational study on mechanism of G-quartet oligonucleotide T40214 selectively targeting Stat3.Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction.Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone.Interleukin-6-induced tethering of STAT3 to the LAP/C/EBPbeta promoter suggests a new mechanism of transcriptional regulation by STAT3.Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies.Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression.A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cellsThe lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by APRF/STAT/3 and other cytokine-inducible nuclear proteins.A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor.Regulation of expression of the rat serine protease inhibitor 2.3 gene by glucocorticoids and interleukin-6. A complex and unusual interplay between positive and negative cis-acting elements.STAT3 signaling in immunity.
P2860
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P2860
The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The interleukin-6-activated ac ...... f transcription (STAT) family.
@en
type
label
The interleukin-6-activated ac ...... f transcription (STAT) family.
@en
prefLabel
The interleukin-6-activated ac ...... f transcription (STAT) family.
@en
P2093
P2860
P356
P1476
The interleukin-6-activated ac ...... f transcription (STAT) family.
@en
P2093
Buschmann J
Heinrich PC
Lottspeich F
Lütticken C
Schindler C
Wegenka UM
P2860
P304
P356
10.1128/MCB.14.5.3186
P407
P577
1994-05-01T00:00:00Z