NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
about
Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2Post-transcriptional Regulation of Immunological Responses through RiboclusteringNonsense-mediated mRNA decay: novel mechanistic insights and biological impactMechanism and regulation of the nonsense-mediated decay pathwayLong-Range Regulation of V(D)J RecombinationNonsense-mediated mRNA decay: inter-individual variability and human diseasePhysiological basis of copper tolerance of Saccharomyces cerevisiae nonsense-mediated mRNA decay mutants.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryIntrons in UTRs: why we should stop ignoring themAttenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppressionEukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanismsUPF2 is a critical regulator of liver development, function and regenerationOut-of-frame T cell receptor beta transcripts are eliminated by multiple pathways in vivoCompound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome.Contribution of copy number variants involving nonsense-mediated mRNA decay pathway genes to neuro-developmental disorders.Function and pathological implications of exon junction complex factor Y14The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay.High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutationsFrame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruptionNonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis.Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.When a ribosome encounters a premature termination codon.Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progressionPost-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decayNonsense-mediated RNA decay: at the 'cutting edge' of regulated snoRNA productionHuman nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent mannerTranscriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability.RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome.Alternative RNA structure-coupled gene regulations in tumorigenesis.Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay.Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infectionPerturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice.Distinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing.Widespread use of non-productive alternative splice sites in Saccharomyces cerevisiaeNonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question.Suppression of nonsense mutations as a therapeutic approach to treat genetic diseases.A novel role for hSMG-1 in stress granule formation
P2860
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P2860
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
NMD is essential for hematopoi ...... programmed DNA rearrangements.
@en
type
label
NMD is essential for hematopoi ...... programmed DNA rearrangements.
@en
prefLabel
NMD is essential for hematopoi ...... programmed DNA rearrangements.
@en
P2093
P2860
P50
P356
P1433
P1476
NMD is essential for hematopoi ...... programmed DNA rearrangements.
@en
P2093
Claus Nerlov
Finn Cilius Nielsen
Inge Damgaard
Kim Theilgaard-Mönch
Lina A Thoren
P2860
P304
P356
10.1101/GAD.468808
P577
2008-05-01T00:00:00Z