Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta.

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The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A Rewiring of cellular membrane homeostasis by picornaviruses.Enterovirus 3A facilitates viral replication by promoting PI4KB-ACBD3 interaction.

P2860

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P2860

Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta.

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http://www.wikidata.org/entity/Q38329269

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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2013年學術文章

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name

Fitness and virulence of a cox ...... sitol 4-kinase class III beta.

@en

type

Item

label

Fitness and virulence of a cox ...... sitol 4-kinase class III beta.

@en

prefLabel

Fitness and virulence of a cox ...... sitol 4-kinase class III beta.

@en

P1476

Fitness and virulence of a cox ...... sitol 4-kinase class III beta.

@en

P2093

Erik Verbeken

http://www.w3.org/2001/XMLSchema#string

Hilde M van der Schaar

http://www.w3.org/2001/XMLSchema#string

Kjerstin H W Lanke

http://www.w3.org/2001/XMLSchema#string

Martin Andrews

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication.

A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ.

A bifunctional anti-enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection.

The antiviral compound enviroxime targets the 3A coding region of rhinovirus and poliovirus.

Sequence determinants of 3A-mediated resistance to enviroxime in rhinoviruses and enteroviruses.

Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.

Inflammatory rather than infectious insults play a role in exocrine tissue damage in a mouse model for coxsackievirus B4-induced pancreatitis.

Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime.

Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis

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3048-3051

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scholarly article

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10.1128/JVI.03177-13

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Pieter Leyssen

Q56378465

Hendrik Jan Thibaut

Frank J M van Kuppeveld

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2013-12-26T00:00:00Z

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24371067

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P921

Coxsackievirus

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3958056

http://www.w3.org/2001/XMLSchema#string

Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta.

about

P2860

P2860

Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

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P698

P921

P932