Induced fit or conformational selection? The role of the semi-closed state in the maltose binding protein
about
Minimum free energy path of ligand-induced transition in adenylate kinaseConformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific CharacteristicsLigand concentration regulates the pathways of coupled protein folding and binding.Utilizing a dynamical description of IspH to aid in the development of novel antimicrobial drugsQuantitatively characterizing the ligand binding mechanisms of choline binding protein using Markov state model analysisEvidence of conformational selection driving the formation of ligand binding sites in protein-protein interfacesCoevolutionary signals across protein lineages help capture multiple protein conformations.Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding.Both protein dynamics and ligand concentration can shift the binding mechanism between conformational selection and induced fitExploration of multi-state conformational dynamics and underlying global functional landscape of maltose binding protein.Equilibrium fluctuations of a single folded protein reveal a multitude of potential cryptic allosteric sites."Gate-keeper" residues and active-site rearrangements in DNA polymerase μ help discriminate non-cognate nucleotides.Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA.Protein Conformational Changes Are Detected and Resolved Site Specifically by Second-Harmonic Generation.Conformational Dynamics of apo-GlnBP Revealed by Experimental and Computational Analysis.Conformational selection and induced fit for RNA polymerase and RNA/DNA hybrid backtracked recognition.Implicit ligand theory: rigorous binding free energies and thermodynamic expectations from molecular docking.Perspective: pre-chemistry conformational changes in DNA polymerase mechanismsCompetitive interactions of ligands and macromolecular crowders with maltose binding protein.Conformational selection is a dominant mechanism of ligand bindingInterplay between conformational selection and induced fit in multidomain protein-ligand binding probed by paramagnetic relaxation enhancement.How maltose influences structural changes to bind to maltose-binding protein: results from umbrella sampling simulation.High-affinity disaccharide binding by tricyclic synthetic lectins.Substrate transport activation is mediated through second periplasmic loop of transmembrane protein MalF in maltose transport complex of Escherichia coliFlexible receptor docking for drug discovery.An integrated perspective on RNA aptamer ligand-recognition models: clearing muddy waters.dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state.Osmolyte-Like Stabilizing Effects of Low GdnHCl Concentrations on d-Glucose/d-Galactose-Binding Protein.Mechanism of mRNA-STAR domain interaction: Molecular dynamics simulations of Mammalian Quaking STAR protein.A single-molecule dissection of ligand binding to a protein with intrinsic dynamics.Kink turn sRNA folding upon L7Ae binding using molecular dynamics simulations.Recognition between a short unstructured peptide and a partially folded fragment leads to the thioredoxin fold sharing native-like dynamics.
P2860
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P2860
Induced fit or conformational selection? The role of the semi-closed state in the maltose binding protein
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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name
Induced fit or conformational ...... in the maltose binding protein
@en
type
label
Induced fit or conformational ...... in the maltose binding protein
@en
prefLabel
Induced fit or conformational ...... in the maltose binding protein
@en
P2860
P356
P1433
P1476
Induced fit or conformational ...... in the maltose binding protein
@en
P2093
Barry J Grant
Denis Bucher
P2860
P304
10530-10539
P356
10.1021/BI201481A
P407
P577
2011-11-10T00:00:00Z