Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells.
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ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cellsHuR regulates p21 mRNA stabilization by UV lightMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationSTAT3 inhibitors for cancer therapy: Have all roads been explored?Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1aSTAT3 as a therapeutic target in head and neck cancerAlterations of Notch/Jagged mRNA and protein expression after partial hepatectomy in ratsSTAT3 deletion sensitizes cells to oxidative stressCaspase-dependent proteolytic cleavage of STAT3alpha in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines.Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene.Interleukin 6 and liver regenerationBone status in patients with epilepsy: relationship to markers of bone remodeling.Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice.The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation.Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines.Dual effects of hepatitis C virus Core protein on the transcription of cyclin-dependent kinase inhibitor p21 gene.Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.The leukemia inhibitory factor (LIF) and p21 mediate the TGFβ tumor suppressive effects in human cutaneous melanomaThe Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers.Molecular and cellular mechanisms of the anabolic effect of intermittent PTHCellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention.The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain.Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway.FGFR3 has tumor suppressor properties in cells with epithelial phenotype.Osteoblast physiology in normal and pathological conditions.Tuning the orchestra: transcriptional pathways controlling axon regenerationOxygen regulates molecular mechanisms of cancer progression and metastasis.STAT3 Target Genes Relevant to Human Cancers.Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1.Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility.Opposite regulation of myc and p21waf1 transcription by STAT3 proteins.A novel anti-viral role for STAT3 in IFN-α signalling responses.Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathwaysConcomitant activation of the PI3K/Akt and ERK1/2 signalling is involved in cyclic compressive force-induced IL-6 secretion in MLO-Y4 cells.Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3.Co-activator SRC-1 is dispensable for transcriptional control by STAT3.
P2860
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P2860
Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Transcriptional activation of ...... s on human osteoblastic cells.
@en
type
label
Transcriptional activation of ...... s on human osteoblastic cells.
@en
prefLabel
Transcriptional activation of ...... s on human osteoblastic cells.
@en
P2093
P356
P1476
Transcriptional activation of ...... s on human osteoblastic cells.
@en
P2093
Manolagas SC
O'Brien CA
Roberson PK
P304
21137-21144
P356
10.1074/JBC.273.33.21137
P407
P577
1998-08-01T00:00:00Z