Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.
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Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteinsGenomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndromeMRP3, an organic anion transporter able to transport anti-cancer drugsIn vivo N-glycosylation of the mep2 high-affinity ammonium transporter of Saccharomyces cerevisiae reveals an extracytosolic N-terminus.Subcellular localization and functional expression of the glycerol uptake protein 1 (GUP1) of Saccharomyces cerevisiae tagged with green fluorescent proteinCharacterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membraneSingle amino acid substitution of rat MRP2 results in acquired transport activity for taurocholateMembrane topology and insertion of membrane proteins: search for topogenic signalsMRP3: a molecular target for human glioblastoma multiforme immunotherapy.Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and traffickingRecombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas.The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function.Requirement of the N-terminal extension for vacuolar trafficking and transport activity of yeast Ycf1p, an ATP-binding cassette transporter.ABC multidrug transporters: structure, function and role in chemoresistance.Photoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4)The MRP family of drug efflux pumps.ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening.Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transportEpitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs.Role of efflux pumps and metabolising enzymes in drug delivery.Membrane topology of human ABC proteins.The multidrug resistance-associated protein (MRP/ABCC) subfamily of ATP-binding cassette transporters in plants.Substrate recognition and transport by multidrug resistance protein 1 (ABCC1).CpABC, a Cryptosporidium parvum ATP-binding cassette protein at the host-parasite boundary in intracellular stages.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.Membrane expression of MRP-1, but not MRP-1 splicing or Pgp expression, predicts survival in patients with ESFT.Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport.Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3.NMR and EPR studies of membrane transporters.Multidrug resistance associated proteins in multidrug resistance.Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1.Determinant of the extracellular location of the N-terminus of human multidrug-resistance-associated protein.The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.Natural product modulators to overcome multidrug resistance in cancer.Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23.
P2860
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P2860
Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Membrane topology of the multi ...... n extracytosolic NH2 terminus.
@en
type
label
Membrane topology of the multi ...... n extracytosolic NH2 terminus.
@en
prefLabel
Membrane topology of the multi ...... n extracytosolic NH2 terminus.
@en
P2093
P2860
P356
P1476
Membrane topology of the multi ...... an extracytosolic NH2 terminus
@en
P2093
D R Hipfner
E M Leslie
J H Gerlach
K C Almquist
R G Deeley
P2860
P304
23623-23630
P356
10.1074/JBC.272.38.23623
P407
P50
P577
1997-09-01T00:00:00Z