Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. - Wikidata - awgldk - TriplyDB

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

http://www.wikidata.org/entity/Q38343552

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Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2 Gadd45 stress sensors in malignancy and leukemia The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis Aberrant Wnt Signaling in Leukemia Mnk kinase pathway: Cellular functions and biological outcomes Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and Treatment The RUNX genes: gain or loss of function in cancer The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARα WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling Oncogenic pathways of AML1-ETO in acute myeloid leukemia: multifaceted manipulation of marrow maturation.Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival Runx expression is mitogenic and mutually linked to Wnt activity in blastula-stage sea urchin embryos Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC β-catenin induces expression of prohibitin gene in acute leukemic cells Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion.Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia.The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.Myc roles in hematopoiesis and leukemia The transcription factor E74-like factor controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow.The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia.Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia.Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.Oncogenesis and cancer stem cells: current opinions and future directions.Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression.Clinical strategies for expansion of haematopoietic stem cells.PAK1 is a therapeutic target in acute myeloid leukemia and myelodysplastic syndrome.The elements of human cyclin D1 promoter and regulation involved.Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia.Gatekeeper pathways and cellular background in the pathogenesis and therapy of AML.

P2860

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P2860

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

http://www.wikidata.org/entity/Q38343552

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Translocation products in acut ...... athway in hematopoietic cells.

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Translocation products in acut ...... athway in hematopoietic cells.

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Translocation products in acut ...... athway in hematopoietic cells.

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MCB.24.7.2890-2904.2004

P1433

Molecular and Cellular Biology

P1476

Translocation products in acut ...... pathway in hematopoietic cells

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P2093

Björn Steffen

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Bülent Sargin

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Carsten Müller-Tidow

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Elena Puccetti

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Gabriele Köhler

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H Phillip Koeffler

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Hubert Serve

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Lara Tickenbrock

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Matthias Stelljes

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Ping Ji

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P2860

Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias

Inhibition of adipogenesis by Wnt signaling

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

Identification of c-MYC as a target of the APC pathway

MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties

Use of chromatin immunoprecipitation to clone novel E2F target promoters

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

Significance analysis of microarrays applied to the ionizing radiation response

Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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2890-2904

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10.1128/MCB.24.7.2890-2904.2004

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24

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Sven Diederichs

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8677237

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15024077

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371102

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