Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences.
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How are model protein structures distributed in sequence space?Substrate specificity of trypsin investigated by using a genetic selectionDNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolutionAn algorithm for protein engineering: simulations of recursive ensemble mutagenesisSimulating evolution by gene duplication of protein features that require multiple amino acid residuesPolymer principles and protein foldingStructure of a protein G helix variant suggests the importance of helix propensity and helix dipole interactions in protein designStructural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold OptimizationTheory for protein mutability and biogenesisScoring functions for computational algorithms applicable to the design of spiked oligonucleotides.Combinatorial mutagenesis analysis of residues in the channel constriction loop L3 and neighbouring beta-strands in the LamB glycoporin of Escherichia coli.Patterned library analysis: a method for the quantitative assessment of hypotheses concerning the determinants of protein structure.Principles of protein folding--a perspective from simple exact models.Optimal sequence selection in proteins of known structure by simulated evolution.Constructing amino acid residue substitution classes maximally indicative of local protein structure.The Shannon information entropy of protein sequences.Combinatorial codons: a computer program to approximate amino acid probabilities with biased nucleotide usage.Computational method to reduce the search space for directed protein evolution.Randomization of the receptor alpha chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop.Investigating and Engineering Enzymes by Genetic Selection.Peptide display libraries: design and construction.Designing gene libraries from protein profiles for combinatorial protein experiments.Assembly of designed oligonucleotides as an efficient method for gene recombination: a new tool in directed evolution.Chiral mutagenesis of insulin. Foldability and function are inversely regulated by a stereospecific switch in the B chainStabilizing the subtilisin BPN' pro-domain by phage display selection: how restrictive is the amino acid code for maximum protein stability?A combinatorial library for the binuclear metal center of bacterial phosphotriesterase.Combinatorial redesign of the DNA binding specificity of a prokaryotic helix-turn-helix repressor.Massive sequence perturbation of a small protein.Statistical theory for protein ensembles with designed energy landscapes.Selecting folded proteins from a library of secondary structural elements.Revisiting the myths of protein interior: studying proteins with mass-fractal hydrophobicity-fractal and polarizability-fractal dimensionsPRP5: a helicase-like protein required for mRNA splicing in yeastThe use of biosensor technology for the engineering of antibodies and enzymes.Probing the CD lumenal loop region of the D2 protein of photosystem II in Synechocystis sp. strain PCC 6803 by combinatorial mutagenesis.Site-saturation mutagenesis: a powerful tool for structure-based design of combinatorial mutation libraries.Identifying determinants of folding and activity for a protein of unknown structure.Lattice model for rapidly folding protein-like heteropolymersMutational analysis of ligand binding activity of beta 2 adrenergic receptor expressed in Escherichia coliGenetic analysis of bacteriophage P22 lysozyme structure.Intragenic suppressors of folding defects in the P22 tailspike protein.
P2860
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P2860
Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Combinatorial cassette mutagen ...... content of protein sequences.
@en
type
label
Combinatorial cassette mutagen ...... content of protein sequences.
@en
prefLabel
Combinatorial cassette mutagen ...... content of protein sequences.
@en
P356
P1433
P1476
Combinatorial cassette mutagen ...... content of protein sequences.
@en
P2093
Reidhaar-Olson JF
P356
10.1126/SCIENCE.3388019
P407
P577
1988-07-01T00:00:00Z