Identification of target genes of the p16INK4A-pRB-E2F pathway.
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Gene expression analysis of forskolin treated basilar papillae identifies microRNA181a as a mediator of proliferation.Bmi1, stem cells, and senescence regulationmiR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elementsTherapeutic targeting of replicative immortalityLamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biologyTranscriptional control of stem cell fate by E2Fs and pocket proteinsDifferential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell modelsiRNA-mediated gene silencing: a global genome view.Mining published lists of cancer related microarray experiments: identification of a gene expression signature having a critical role in cell-cycle control.Breast tumor copy number aberration phenotypes and genomic instabilityHuman VRK1 is an early response gene and its loss causes a block in cell cycle progression.Meta-analysis and gene set enrichment relative to er status reveal elevated activity of MYC and E2F in the "basal" breast cancer subgroup.Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data.p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.Differential gene expression profile of retinoblastoma compared to normal retinaTailoring to RB: tumour suppressor status and therapeutic response.A cancer-specific transcriptional signature in human neoplasia.Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.Down-regulation of the oncogene cyclin D1 increases migratory capacity in breast cancer and is linked to unfavorable prognostic features.RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response.pRb-Independent growth arrest and transcriptional regulation of E2F target genesThe histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells.RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells.ERK activity and G1 phase progression: identifying dispensable versus essential activities and primary versus secondary targetsLocalizing hotspots of antisense transcription.CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive RhabdomyosarcomaHyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cellsA Skp2 autoinduction loop and restriction point control.p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesisIntegrative genomics identified RFC3 as an amplified candidate oncogene in esophageal adenocarcinoma.Gene expression reveals two distinct groups of anal carcinomas with clinical implicationsp16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.The role of the retinoblastoma/E2F1 tumor suppressor pathway in the lesion recognition step of nucleotide excision repair.The cyclin-dependent kinase inhibitor p16INK4a physically interacts with transcription factor Sp1 and cyclin-dependent kinase 4 to transactivate microRNA-141 and microRNA-146b-5p spontaneously and in response to ultraviolet light-induced DNA damage.Systems biology-based identification of crosstalk between E2F transcription factors and the Fanconi anemia pathway.Positive-feedback loops in cell cycle progression.Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.Promotion of cell proliferation by the proto-oncogene DEK enhances oral squamous cell carcinogenesis through field cancerizationp16(INK4A) inhibits the pro-metastatic potentials of osteosarcoma cells through targeting the ERK pathway and TGF-β1.
P2860
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P2860
Identification of target genes of the p16INK4A-pRB-E2F pathway.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Identification of target genes of the p16INK4A-pRB-E2F pathway.
@en
type
label
Identification of target genes of the p16INK4A-pRB-E2F pathway.
@en
prefLabel
Identification of target genes of the p16INK4A-pRB-E2F pathway.
@en
P2860
P356
P1476
Identification of target genes of the p16INK4A-pRB-E2F pathway
@en
P2093
Richard Vernell
P2860
P304
46124-46137
P356
10.1074/JBC.M304930200
P407
P577
2003-08-15T00:00:00Z