The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation.
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The transcription factor p53: not a repressor, solely an activatorDistinct roles for mitogen-activated protein kinase phosphatase-1 (MKP-1) and ERK-MAPK in PTH1R signaling during osteoblast proliferation and differentiationPBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21Role of DUSP1/MKP1 in tumorigenesis, tumor progression and therapyActivation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothersExit from arsenite-induced mitotic arrest is p53 dependentAlterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac developmentTAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53.Extracellular signal-regulated kinase 1/2 activation, via downregulation of mitogen-activated protein kinase phosphatase 1, mediates sex differences in desoxycorticosterone acetate-salt hypertension vascular reactivity.Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment.AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma.The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway.Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress.Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cellsInvestigating the Role of TNF-α and IFN-γ Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated MacrophagesDUSPs, to MAP kinases and beyond.MKP-1 antagonizes C/EBPβ activity and lowers the apoptotic threshold after ischemic injuryMitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease.Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7.Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions.The dark side of a tumor suppressor: anti-apoptotic p53.Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage.Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy.Obstructive sleep apnea and intermittent hypoxia increase expression of dual specificity phosphatase 1.p53 predominantly regulates IL-6 production and suppresses synovial inflammation in fibroblast-like synoviocytes and adjuvant-induced arthritisWhat's new in p53?Targeting DUSPs in glioblastomas - wielding a double-edged sword?Genetics of breast cancer bone metastasis: a sequential multistep pattern.Expression Profiling of the MAP Kinase Phosphatase Family Reveals a Role for DUSP1 in the Glioblastoma Stem Cell Niche.DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins.Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells.Expression of the class II tumor suppressor gene RIG1 is directly regulated by p53 tumor suppressor in cancer cell lines.Epstein-Barr virus-encoded LMP1 triggers regulation of the ERK-mediated Op18/stathmin signaling pathway in association with cell cycle.Microarray expression profiling in 6-hydroxydopamine-induced dopaminergic neuronal cell death.p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis.Epac1, PDE4, and PKC protein expression and their association with AKAP95, Cx43, and cyclinD2/E1 in breast cancer tissuesRegulation of angiopoietin-1/Tie-2 receptor signaling in endothelial cells by dual-specificity phosphatases 1, 4, and 5.Heparin treatment of vascular smooth muscle cells results in the synthesis of the dual-specificity phosphatase MKP-1.Cross-talk between the p38alpha and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation.
P2860
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P2860
The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
@zh-hant
name
The phosphatase MKP1 is a tran ...... lved in cell cycle regulation.
@en
type
label
The phosphatase MKP1 is a tran ...... lved in cell cycle regulation.
@en
prefLabel
The phosphatase MKP1 is a tran ...... lved in cell cycle regulation.
@en
P2093
P2860
P356
P1476
The phosphatase MKP1 is a tran ...... lved in cell cycle regulation.
@en
P2093
Gen Sheng Wu
Jun-Ying Zhou
Larry H Matherly
Maoxiang Li
P2860
P304
41059-41068
P356
10.1074/JBC.M307149200
P407
P577
2003-07-29T00:00:00Z