The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism.
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Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanismTranscriptional up-regulation and activation of initiating caspases in experimental glaucomaDownregulation of Thy1 in retinal ganglion cells in experimental glaucoma.Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival.Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation.Identification of candidate genes with pro-apoptotic properties by functional screening of randomly fragmented cDNA libraries.Single-nucleotide polymorphisms in the p53 signaling pathway.Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis.Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator.Exploring SNP-SNP interactions and colon cancer risk using polymorphism interaction analysis.Transcriptional regulation of pro-apoptotic protein kinase Cdelta: implications for oxidative stress-induced neuronal cell death.DNA methylation in thyroid tumorigenesis.Functional interaction of E1AF and Sp1 in glioma invasion.Transcriptional control analyses of the Xiphophorus melanoma oncogene.Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells.Chronic Social Stress and Ethanol Increase Expression of KLF11, a Cell Death Mediator, in Rat BrainIn search of tumor suppressing functions of meninRole of caspases in 5-FU and selenium-induced growth inhibition of colorectal cancer cellsCaspases and cancer.Evading apoptosis in cancer.Essential role of caspase-8 in p53/p73-dependent apoptosis induced by etoposide in head and neck carcinoma cells.Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sitesTAp63alpha induces apoptosis by activating signaling via death receptors and mitochondriaThe up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1.Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice.Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells.CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter.Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.DNA topoisomerase II poison TAS-103 transactivates GC-box-dependent transcription via acetylation of Sp1.Reversal of 5-flouroucial resistance by adenovirus-mediated transfer of wild-type p53 gene in multidrug-resistant human colon carcinoma LoVo/5-FU cells.A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.p63 regulates the caspase-8-FLIP apoptotic pathway in epidermis.The role of bronchial epithelial cell apoptosis in the pathogenesis of COPD.
P2860
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P2860
The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
The human caspase-8 promoter s ...... by a p53-dependent mechanism.
@en
type
label
The human caspase-8 promoter s ...... by a p53-dependent mechanism.
@en
prefLabel
The human caspase-8 promoter s ...... by a p53-dependent mechanism.
@en
P2093
P2860
P356
P1476
The human caspase-8 promoter s ...... by a p53-dependent mechanism.
@en
P2093
Christian Trautwein
Michael P Manns
Nadine Groger
P2860
P304
27593-27604
P356
10.1074/JBC.M304077200
P407
P577
2003-05-14T00:00:00Z