The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.
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Enhancers: five essential questionsTIF1gamma controls erythroid cell fate by regulating transcription elongationc-Myc regulates transcriptional pause releaseCTCF-dependent enhancer-blocking by alternative chromatin loop formationMammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genesA new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongationFrom stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modificationsGenome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cyclesControlling long-range genomic interactions at a native locus by targeted tethering of a looping factorAn unmethylated 3' promoter-proximal region is required for efficient transcription initiationMultiple functions of Ldb1 required for beta-globin activation during erythroid differentiationSpecific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongationSubcellular transport of EKLF and switch-on of murine adult beta maj globin gene transcription.The chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation.Developmental stage differences in chromatin subdomains of the beta-globin locus.Role of LDB1 in the transition from chromatin looping to transcription activation.USF and NF-E2 cooperate to regulate the recruitment and activity of RNA polymerase II in the beta-globin gene locus.The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes.Genomic imprinting recapitulated in the human beta-globin locus.Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.Moonshine illuminates a developmental role for regulated transcription elongationSumoylation of p45/NF-E2: nuclear positioning and transcriptional activation of the mammalian beta-like globin gene locusReplication and transcription: shaping the landscape of the genome.Enhancers: the abundance and function of regulatory sequences beyond promoters.Transcriptional control of erythropoiesis: emerging mechanisms and principles.A distant upstream locus control region is critical for expression of the Kit receptor gene in mast cellsA major role for the TATA box in recruitment of chromatin modifying complexes to a globin gene promoter.Uncovering enhancer functions using the α-globin locus.Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequencesDynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid developmentLong-Range Chromatin InteractionsThe hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation.Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain.Effect of Interaction between Chromatin Loops on Cell-to-Cell Variability in Gene ExpressionA structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformationDNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer functionDynamic enhancer-gene body contacts during transcription elongation.Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network.
P2860
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P2860
The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
The beta -globin locus control ...... tion initiation to elongation.
@en
type
label
The beta -globin locus control ...... tion initiation to elongation.
@en
prefLabel
The beta -globin locus control ...... tion initiation to elongation.
@en
P2093
P2860
P356
P1433
P1476
The beta -globin locus control ...... tion initiation to elongation.
@en
P2093
Jessica Halow
M A Bender
Mark Groudine
Tomoyuki Sawado
P2860
P304
P356
10.1101/GAD.1072303
P577
2003-04-02T00:00:00Z