The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation. - Wikidata - awgldk - TriplyDB

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

http://www.wikidata.org/entity/Q38356015

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Enhancers: five essential questions TIF1gamma controls erythroid cell fate by regulating transcription elongation c-Myc regulates transcriptional pause release CTCF-dependent enhancer-blocking by alternative chromatin loop formation Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor An unmethylated 3' promoter-proximal region is required for efficient transcription initiation Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1 Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation Subcellular transport of EKLF and switch-on of murine adult beta maj globin gene transcription.The chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation.Developmental stage differences in chromatin subdomains of the beta-globin locus.Role of LDB1 in the transition from chromatin looping to transcription activation.USF and NF-E2 cooperate to regulate the recruitment and activity of RNA polymerase II in the beta-globin gene locus.The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes.Genomic imprinting recapitulated in the human beta-globin locus.Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture.Moonshine illuminates a developmental role for regulated transcription elongation Sumoylation of p45/NF-E2: nuclear positioning and transcriptional activation of the mammalian beta-like globin gene locus Replication and transcription: shaping the landscape of the genome.Enhancers: the abundance and function of regulatory sequences beyond promoters.Transcriptional control of erythropoiesis: emerging mechanisms and principles.A distant upstream locus control region is critical for expression of the Kit receptor gene in mast cells A major role for the TATA box in recruitment of chromatin modifying complexes to a globin gene promoter.Uncovering enhancer functions using the α-globin locus.Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development Long-Range Chromatin Interactions The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation.Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain.Effect of Interaction between Chromatin Loops on Cell-to-Cell Variability in Gene Expression A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation DNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer function Dynamic enhancer-gene body contacts during transcription elongation.Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network.

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The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

http://www.wikidata.org/entity/Q38356015

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-sg

2003年學術文章

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2003年學術文章

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2003年學術文章

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name

The beta -globin locus control ...... tion initiation to elongation.

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type

label

The beta -globin locus control ...... tion initiation to elongation.

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prefLabel

The beta -globin locus control ...... tion initiation to elongation.

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Genes & Development

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The beta -globin locus control ...... tion initiation to elongation.

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P2093

Jessica Halow

http://www.w3.org/2001/XMLSchema#string

M A Bender

http://www.w3.org/2001/XMLSchema#string

Mark Groudine

http://www.w3.org/2001/XMLSchema#string

Tomoyuki Sawado

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P2860

The myoD gene family: nodal point during specification of the muscle cell lineage

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

Isolation of cDNA encoding the human NF-E2 protein

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene

Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter.

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulation

Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

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1009-1018

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scholarly article

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10.1101/GAD.1072303

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8

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17

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2003-04-02T00:00:00Z

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10824166

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12672691

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196035

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