DNA-binding mechanism of O6-alkylguanine-DNA alkyltransferase. Effects of protein and DNA alkylation on complex stability.
about
Hexahistidine-tag-specific optical probes for analyses of proteins and their interactionsFlipping of alkylated DNA damage bridges base and nucleotide excision repairAlkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation- interactionsA two-step nucleotide-flipping mechanism enables kinetic discrimination of DNA lesions by AGTCharacterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase.Combination of native and denaturing PAGE for the detection of protein binding regions in long fragments of genomic DNA.Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.Insight into the cooperative DNA binding of the O⁶-alkylguanine DNA alkyltransferase.Repair of O6-methylguanine adducts in human telomeric G-quadruplex DNA by O6-alkylguanine-DNA alkyltransferase.Alkyltransferase-like proteins: molecular switches between DNA repair pathways.DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapyHuman variants of O6-alkylguanine-DNA alkyltransferase.Borrelia burgdorferi cp32 BpaB modulates expression of the prophage NucP nuclease and SsbP single-stranded DNA-binding protein.Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable proteinApparent directional scanning for DNA repair.Cooperative cluster formation, DNA bending and base-flipping by O6-alkylguanine-DNA alkyltransferase.Lesion-specific DNA-binding and repair activities of human O⁶-alkylguanine DNA alkyltransferase.Direct reversal of DNA alkylation damage.S-alkylthiolation of O6-methylguanine-DNA-methyltransferase (MGMT) to sensitize cancer cells to anticancer therapy.Alkyltransferase-mediated toxicity of 1,3-butadiene diepoxide.Tumor-associated mutations in O⁶ -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality.Kinetics of O(6)-pyridyloxobutyl-2'-deoxyguanosine repair by human O(6)-alkylguanine DNA alkyltransferase.Structural and biophysical characterization of the proteins interacting with the herpes simplex virus 1 origin of replication.Topologies of complexes containing O6-alkylguanine-DNA alkyltransferase and DNA.Mechanism of strand-specific smooth muscle alpha-actin enhancer interaction by purine-rich element binding protein B (Purbeta).Cytosine methylation effects on the repair of O6-methylguanines within CG dinucleotides.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.An O6-methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein.Interactions of human O6-alkylguanine-DNA alkyltransferase (AGT) with short single-stranded DNAs.Kinetic analysis of steps in the repair of damaged DNA by human O6-alkylguanine-DNA alkyltransferase.6-Carboxyfluorescein and structurally similar molecules inhibit DNA binding and repair by O⁶-alkylguanine DNA alkyltransferaseInteractions of human O(6)-alkylguanine-DNA alkyltransferase (AGT) with short double-stranded DNAsResolving the contributions of two cooperative mechanisms to the DNA binding of AGT.Activity and regulation of archaeal DNA alkyltransferase: conserved protein involved in repair of DNA alkylation damage.Electrophoretic mobility shift assay (EMSA) for detecting protein-nucleic acid interactions.Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O-Alkylguanine-DNA Alkyltransferase Activity.Synthesis and characterization of an O(6)-2'-deoxyguanosine-alkyl-O(6)-2'-deoxyguanosine interstrand cross-link in a 5'-GNC motif and repair by human O(6)-alkylguanine-DNA alkyltransferase.Mutations that probe the cooperative assembly of O⁶-alkylguanine-DNA alkyltransferase complexes.Active-site alkylation destabilizes human O6-alkylguanine DNA alkyltransferase.DNA binding and nucleotide flipping by the human DNA repair protein AGT.
P2860
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P2860
DNA-binding mechanism of O6-alkylguanine-DNA alkyltransferase. Effects of protein and DNA alkylation on complex stability.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
DNA-binding mechanism of O6-al ...... kylation on complex stability.
@en
type
label
DNA-binding mechanism of O6-al ...... kylation on complex stability.
@en
prefLabel
DNA-binding mechanism of O6-al ...... kylation on complex stability.
@en
P2093
P2860
P356
P1476
DNA-binding mechanism of O6-al ...... kylation on complex stability.
@en
P2093
Anthony E Pegg
Joseph J Rasimas
Michael G Fried
P2860
P304
P356
10.1074/JBC.M211854200
P407
P577
2002-12-20T00:00:00Z