Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival.
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FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinomaGrainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytesGrainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanismRegulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cellsMel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cellsLingual Epithelial Stem Cells and Organoid Culture of ThemPolycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsExpression of Bmi-1 is a prognostic marker in bladder cancerThe Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival.Bmi-1 expression predicts prognosis in squamous cell carcinoma of the tongue.p53 Loss synergizes with estrogen and papillomaviral oncogenes to induce cervical and breast cancers.Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domainIdentification and characterization of Bmi-1-responding element within the human p16 promoter.The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors.Clinicopathologic characteristics of high expression of Bmi-1 in esophageal adenocarcinoma and squamous cell carcinoma.BMI1, stem cell factor acting as novel serum-biomarker for Caucasian and African-American prostate cancer.RNAi-mediated silencing of the Bmi-1 gene causes growth inhibition and enhances doxorubicin-induced apoptosis in MCF-7 cells.Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis.Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.BMI1 polycomb group protein acts as a master switch for growth and death of tumor cells: regulates TCF4-transcriptional factor-induced BCL2 signaling.Bmi1 drives stem-like properties and is associated with migration, invasion, and poor prognosis in tongue squamous cell carcinoma.Regulation of the potential marker for intestinal cells, Bmi1, by β-catenin and the zinc finger protein KLF4: implications for colon cancer.The Stem Cell Marker Bmi-1 Is Sensitive in Identifying Early Lesions of Carcinoma ex Pleomorphic AdenomaNuclear BMI-1 expression in laryngeal carcinoma correlates with lymph node pathological status.The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (-) epigallocatechin-3-gallate suppression of skin cancer cell survivalMicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene.Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma.Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.Efavirenz induces autophagy and aberrant differentiation in normal human keratinocytes.Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cellsBMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases.Distinct population of highly malignant cells in a head and neck squamous cell carcinoma cell line established by xenograft model.Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer.Epigenetic factors in cancer development: polycomb group proteins.Can immunohistochemistry serve as an alternative to subjective histopathological diagnosis of oral epithelial dysplasia?The role of polycomb repressive complexes in biliary tract cancer.Bispecific antibody suppresses osteosarcoma aggressiveness through regulation of NF-κB signaling pathway.Targeting of BMI-1 with PTC-209 shows potent anti-myeloma activity and impairs the tumour microenvironment.Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells.Epigenetic gene regulation by histone demethylases: emerging role in oncogenesis and inflammation.
P2860
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P2860
Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Elevated Bmi-1 expression is a ...... cell replication and survival.
@en
type
label
Elevated Bmi-1 expression is a ...... cell replication and survival.
@en
prefLabel
Elevated Bmi-1 expression is a ...... cell replication and survival.
@en
P2093
P2860
P356
P1476
Elevated Bmi-1 expression is a ...... cell replication and survival.
@en
P2093
R Christensen
P2860
P2888
P304
P356
10.1038/SJ.BJC.6603529
P407
P577
2006-12-19T00:00:00Z
P5875
P6179
1045357520