about
The well-accepted notion that gene amplification contributes to increased expression still remains, after all these years, a reasonable but unproven assumptionPractical aspects of NGS-based pathways analysis for personalized cancer science and medicineEmerging Role of Genomic Rearrangements in Breast Cancer: Applying Knowledge from Other CancersAdvances in the Molecular Analysis of Soft Tissue Tumors and Clinical ImplicationsNTRK gene fusions as novel targets of cancer therapy across multiple tumour typesTargeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentDiscovering and understanding oncogenic gene fusions through data intensive computational approachesChimerDB 3.0: an enhanced database for fusion genes from cancer transcriptome and literature data miningInFusion: Advancing Discovery of Fusion Genes and Chimeric Transcripts from Deep RNA-Sequencing Data.Fluorescence in situ hybridization in surgical pathology: principles and applications.It Is Imperative to Establish a Pellucid Definition of Chimeric RNA and to Clear Up a Lot of Confusion in the Relevant Research.Optical coding of fusion genes using multicolor quantum dots for prostate cancer diagnosis.ChiPPI: a novel method for mapping chimeric protein-protein interactions uncovers selection principles of protein fusion events in cancer.Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target.Two RNAs or DNAs May Artificially Fuse Together at a Short Homologous Sequence (SHS) during Reverse Transcription or Polymerase Chain Reactions, and Thus Reporting an SHS-Containing Chimeric RNA Requires Extra Caution.Efficient generation and reversion of chromosomal translocations using CRISPR/Cas technology.FuGePrior: A novel gene fusion prioritization algorithm based on accurate fusion structure analysis in cancer RNA-seq samples.ChimeRScope: a novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data.Landscape of gene fusions in epithelial cancers: seq and ye shall find.Novel kinase fusion transcripts found in endometrial cancerIdentification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.Genomic and Epigenomic Alterations in CancerTranslocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequencesRecurrent and pathological gene fusions in breast cancer: current advances in genomic discovery and clinical implications.Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic VariationGene fusions in soft tissue tumors: Recurrent and overlapping pathogenetic themesUnderstanding Molecular Landscape of Endometrial Cancer through Next Generation Sequencing: What We Have Learned so Far?Identification of a novel partner gene, KIAA1217, fused to RET: Functional characterization and inhibitor sensitivity of two isoforms in lung adenocarcinomaOverexpression of KLHL23 protein from read-through transcription of PHOSPHO2-KLHL23 in gastric cancer increases cell proliferation.Adenoid cystic carcinoma: emerging role of translocations and gene fusionsA novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival.Recurrent fusion transcripts detected by whole-transcriptome sequencing of 120 primary breast cancer samples.Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles.Proteogenomics for understanding oncology: recent advances and future prospects.Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine.The impact of melanoma genetics on treatment response and resistance in clinical and experimental studies.Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.Novel transcription-induced fusion RNAs in prostate cancer.Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The emerging complexity of gene fusions in cancer.
@en
type
label
The emerging complexity of gene fusions in cancer.
@en
prefLabel
The emerging complexity of gene fusions in cancer.
@en
P2860
P356
P1476
The emerging complexity of gene fusions in cancer.
@en
P2093
Bertil Johansson
Felix Mitelman
P2860
P2888
P304
P356
10.1038/NRC3947
P407
P577
2015-06-01T00:00:00Z
P6179
1049444119