Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. - Wikidata - awgldk - TriplyDB

Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.

Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.

http://www.wikidata.org/entity/Q38498581

about

Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8 The Role of fibroblast growth factor receptor substrate 2 (FRS2) in the regulation of two activity levels of the components of the extracellular signal-regulated kinase (ERK) pathway in the mouse epididymis.Jun is required in Isl1-expressing progenitor cells for cardiovascular development Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis.Redundant and dosage sensitive requirements for Fgf3 and Fgf10 in cardiovascular development Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndrome PI3K/mTOR signaling regulates prostatic branching morphogenesis A roadmap to investigate the genetic basis of bicuspid aortic valve and its complications: insights from the International BAVCon (Bicuspid Aortic Valve Consortium).Partitioning the heart: mechanisms of cardiac septation and valve development Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity.Wnt/β-catenin signaling enables developmental transitions during valvulogenesis.FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development.An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.Heart valve development: regulatory networks in development and disease Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia Tissue-tissue interactions during morphogenesis of the outflow tract.Notch and cardiac outflow tract development.Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis.The role of endothelial-mesenchymal transition in development and pathological process.A molecular and genetic outline of cardiac morphogenesis.The functional diversity of essential genes required for mammalian cardiac development.Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and development of the great arteries.Conserved signaling mechanisms in Drosophila heart development.The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation.Endothelial-to-mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awry.Association Between Single Nucleotide Polymorphisms in NFATC1 Signaling Pathway Genes and Susceptibility to Congenital Heart Disease in the Chinese Population.

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P2860

Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.

http://www.wikidata.org/entity/Q38498581

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

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2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

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name

Frs2alpha-deficiency in cardia ...... r outflow tract morphogenesis.

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type

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Frs2alpha-deficiency in cardia ...... r outflow tract morphogenesis.

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Frs2alpha-deficiency in cardia ...... r outflow tract morphogenesis.

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Frs2alpha-deficiency in cardia ...... r outflow tract morphogenesis.

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Anne M Moon

http://www.w3.org/2001/XMLSchema#string

Chunhong Lin

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Fen Wang

http://www.w3.org/2001/XMLSchema#string

James F Martin

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Jue Zhang

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Robert J Schwartz

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Yongsheng Lan

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Yongshun Lin

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Yongyou Zhang

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P2860

Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk

Notch signaling is essential for ventricular chamber development

Cellular signaling by fibroblast growth factor receptors

FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice

Neural crest and cardiovascular development: a 20-year perspective

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

NFAT proteins: key regulators of T-cell development and function

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3611-3622

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10.1242/DEV.025361

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21

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135

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18832393

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