Expression of human cationic trypsinogen with an authentic N terminus using intein-mediated splicing in aminopeptidase P deficient Escherichia coli.
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Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitisGene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active siteProtein surface charge of trypsinogen changes its activation pattern.Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin CPathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitisFunctional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis.Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death.Recent advances in in vivo applications of intein-mediated protein splicing.Chymotrypsin C (caldecrin) stimulates autoactivation of human cationic trypsinogen.Proteolytic activation of human pancreatitis-associated protein is required for peptidoglycan binding and bacterial aggregation.Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutants.Expression of recombinant proteins with uniform N-termini
P2860
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P2860
Expression of human cationic trypsinogen with an authentic N terminus using intein-mediated splicing in aminopeptidase P deficient Escherichia coli.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Expression of human cationic t ...... P deficient Escherichia coli.
@en
type
label
Expression of human cationic t ...... P deficient Escherichia coli.
@en
prefLabel
Expression of human cationic t ...... P deficient Escherichia coli.
@en
P2093
P2860
P1476
Expression of human cationic t ...... P deficient Escherichia coli.
@en
P2093
Edit Szepessy
Miklós Tóth
Orsolya Király
Zoltán Kukor
P2860
P304
P356
10.1016/J.PEP.2006.01.023
P577
2006-02-21T00:00:00Z