Bmp2 controls iron homeostasis in mice independent of Bmp6.

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MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice.Inherited Disorders of Iron Overload MyD88 Regulates the Expression of SMAD4 and the Iron Regulatory Hormone Hepcidin

P2860

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Bmp2 controls iron homeostasis in mice independent of Bmp6.

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2017 nî lūn-bûn

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Bmp2 controls iron homeostasis in mice independent of Bmp6.

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Bmp2 controls iron homeostasis in mice independent of Bmp6.

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Bmp2 controls iron homeostasis in mice independent of Bmp6.

@en

P1476

Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6

@en

P2093

Abraham Bayer

http://www.w3.org/2001/XMLSchema#string

Chia-Yu Wang

http://www.w3.org/2001/XMLSchema#string

Kimberly B Zumbrennen-Bullough

http://www.w3.org/2001/XMLSchema#string

Susanna Canali

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P2860

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

A mouse model of juvenile hemochromatosis.

Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

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1204-1213

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P31

scholarly article

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10.1002/AJH.24888

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Jodie L Babitt

P577

2017-09-25T00:00:00Z

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P698

28815688

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P932

5986189

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Bmp2 controls iron homeostasis in mice independent of Bmp6.

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P2860

P2860

Bmp2 controls iron homeostasis in mice independent of Bmp6.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932