The vertebrate cell kinetochore and its roles during mitosis.
about
Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosisHuman BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCLIS1, CLIP-170's key to the dynein/dynactin pathway.Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathwayAssociation of human kinesin superfamily protein member 4 with BRCA2-associated factor 35Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during mitosisCell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cellsEB1 targets to kinetochores with attached, polymerizing microtubulesThe human chromokinesin Kid is a plus end-directed microtubule-based motorMicrotubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochoresHec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.A new look at kinetochore structure in vertebrate somatic cells using high-pressure freezing and freeze substitutionYeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replicationCytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivationThe centromere geometry essential for keeping mitosis error free is controlled by spindle forcesCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cellsThe small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpointKinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosisFunctional analysis of kinetochore assembly in Caenorhabditis elegans.Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresPericentric heterochromatin becomes enriched with H2A.Z during early mammalian developmentThe chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindlesProbing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.Basic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules.ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochoresFission yeast cells undergo nuclear division in the absence of spindle microtubulesChromosomes can congress to the metaphase plate before biorientation.Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase.CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation.Polyploids require Bik1 for kinetochore-microtubule attachment.Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubulesAurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochoresCohesin defects lead to premature sister chromatid separation, kinetochore dysfunction, and spindle-assembly checkpoint activationTwo mitotic kinesins cooperate to drive sister chromatid separation during anaphaseDepletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachmentsCharacterization of a novel kinetochore protein, CENP-HMurine CENPF interacts with syntaxin 4 in the regulation of vesicular transportUnzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion
P2860
Q21142712-EC49E725-1010-44D8-93FD-EBCF376B5F5BQ22010522-624132DA-719C-4759-8E60-026EBC5FDED6Q24293597-3F66B0C9-C123-4BF9-950D-8BCED8DA70C9Q24301363-EAC4D3F1-1C02-424F-A13A-ABF363A67AE5Q24338369-4BD447B9-9835-4B3A-BBC5-82FE6422E352Q24530209-47ADBE25-DBD3-4696-8ED2-768F94723F46Q24533550-E4FBA5EA-759F-4729-833F-6FFFBC736E35Q24534293-53A6D300-2E34-48AE-A811-282CA5D90B7BQ24541553-1C6E4647-D6DB-4EB9-87B8-E64BFF099D68Q24550989-81AAF124-1130-4C2D-B25C-E44C6AD7429AQ24555706-7C92CC83-8568-4E9D-A124-C7491C23A984Q24557448-3A6C0B4C-1D92-4D06-9C64-6A13E98B43F8Q24607318-4A513A42-3DFF-42AF-BBE0-0BDE09046446Q24608777-037384BD-ED04-40B3-88D9-6D076139E4E4Q24652311-280937A0-DF53-4E4D-B0F0-41D6540F5603Q24654805-8473E694-6CFD-4757-A272-9B3FAEA41864Q24670095-AF62F9B9-46D5-4E3D-96CA-E62A928B05CFQ24674081-D51642E1-3FAF-4F02-B313-2A0F2424E1F9Q24675117-72552906-89CF-4A68-9E6F-224F428BC82BQ24676290-73CF20B6-B203-4186-B320-4CEBAF2593EDQ24679016-60EE44F6-E95C-4B37-92CA-2EE8F2CA1A1AQ24682987-1B9258DD-58F3-4611-BD16-8364987950ADQ24683806-1598CFAB-359A-4802-A2ED-40787F67C3F7Q24685481-5087C432-8D44-49A7-A44F-80CA30E334A5Q24685871-8AA40A32-EE41-47A5-87BB-B6EE19911862Q27305370-31C72708-B036-40DB-8979-8377530FD765Q27310821-422107D9-C73E-4CA7-90AB-208B6D45D333Q27323083-56F1B43C-47A3-4CB6-82F1-64E4AB472AB9Q27332199-00540ED3-CD6A-4DE0-95BE-A5140BA26667Q27929767-35819A53-8469-4216-9BC8-AFAC374603B0Q27932199-99889318-7B48-4AE5-BCFA-C556B107F4AEQ27937672-318B91E8-F951-410A-A28D-79F904ABC330Q28115312-ABF01888-26FF-4E59-B6D7-76220D502389Q28201606-1E7532C5-99B0-4224-B8EA-9E2C26E5EA00Q28219330-96300D94-A4DB-4950-AE68-48C377A6BC35Q28235011-A0E1EA5D-7B63-473B-AACF-55FD66CFE748Q28236606-414FA31A-2C1A-4FE4-9CC2-9950FDB5AFB0Q28591361-21C9A67A-8A5B-4549-B99C-88C0F37604A3Q28593991-AA4E03CE-8442-4697-9DF3-8ADE08875DF0Q28756062-8B3784EB-DCBB-4689-A179-E52E4277E06C
P2860
The vertebrate cell kinetochore and its roles during mitosis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The vertebrate cell kinetochore and its roles during mitosis.
@en
type
label
The vertebrate cell kinetochore and its roles during mitosis.
@en
prefLabel
The vertebrate cell kinetochore and its roles during mitosis.
@en
P2860
P1476
The vertebrate cell kinetochore and its roles during mitosis.
@en
P2093
C L Rieder
E D Salmon
P2860
P304
P356
10.1016/S0962-8924(98)01299-9
P577
1998-08-01T00:00:00Z