BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance. - Wikidata - awgldk - TriplyDB

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

http://www.wikidata.org/entity/Q38776637

about

Higher-Order Chromatin Regulation of Inflammatory Gene Expression Oncogenic senescence: a multi-functional perspective.cGAS is essential for cellular senescence.BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1 Bromodomain 4: a cellular Swiss army knife The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging.The Chromatin Landscape of Cellular Senescence.Cellular senescence in renal ageing and disease.Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseases Targeting Cancer Cells with BET Bromodomain Inhibitors.The role of epigenetics in renal ageing.Super-Enhancer-Driven Transcriptional Dependencies in Cancer.Senescent cells: an emerging target for diseases of ageing.ATRX is a regulator of therapy induced senescence in human cells.Cancer and Aging - the Inflammatory Connection.HMGB2 holds the key to the senescence-associated secretory phenotype.Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation.Cytoplasmic chromatin triggers inflammation in senescence and cancer.Senescence and tumor suppression.Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage.Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition.Senescence and aging: Causes, consequences, and therapeutic avenues.Epigenetic Basis of Cellular Senescence and Its Implications in Aging.Genetic Ablation of p16(Ink4a) Does Not Protect Against Cellular Senescence in Mouse Models of COPD/Emphysema.BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis.Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.Mechanisms and functions of cellular senescence.A novel combination treatment against melanoma with NRAS mutation and therapy resistance.Strategies targeting cellular senescence.Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.

P2860

Q33593001-D89F1A9C-939A-4D76-A7B3-87F2C6FDA519 Q33689160-D0F75C33-DA2E-4EF5-BB8E-CE7E1CCA33EA Q33790789-0E8734E5-B838-477E-BF42-15B5B79EE4E0 Q34048020-9384AEBA-3041-474D-9B91-319B5D39DC8E Q38906390-D25625E8-05AC-4C22-9CFC-576C06C8A0D5 Q38932691-042C2A48-4C44-4762-9F4D-FC3EEB687EED Q38969345-AC334EE5-6D79-4797-B2AD-E62B9CCB739D Q39060497-B271EF24-C60E-4B41-839C-41157466FF42 Q39122209-3DBD72FC-25FD-4B22-8761-F41B2277DD68 Q39141456-43080A0A-EA99-4E30-8354-521FE04C5D4B Q39381492-8E8ABD03-737E-4C2A-8388-38E4021C7660 Q39441366-B8EE2785-5FAD-4E83-A754-BE4C45F8253F Q39449103-0F827F65-9A06-4C5A-8FCB-8CE7F82FC88B Q41565938-2548B007-210E-49F4-B67C-CCE63A338C51 Q41983762-5B9131DA-5A65-4BA3-B7A8-B859E9AC7EDB Q42372261-3066D203-DE60-4EED-BEAC-E2FE23B1B1B7 Q42512025-EFBC5382-B390-449B-9B69-18DA1B94BBEB Q46165767-71C073AD-7B98-4CED-A9F6-FD3AC02AA028 Q47106101-B2FD5F73-C16C-4BF3-B816-A1F78F8A21FD Q47962641-8A47090D-5F37-4B09-A86E-3928FD576023 Q48023755-434DECD6-F2E4-4CA0-B2E7-AA5559476689 Q48347290-66A0983C-51A4-468B-8DD4-344052605A26 Q49523811-8AD3B7E7-1F11-4DE7-9C00-20D7026CA40C Q49976677-F9509206-041D-47A9-8264-EA7A49C975EB Q50055635-E554B9D5-B9D5-40BF-8F42-9DD08D6CE356 Q51733364-18E19D08-6CC3-4F68-88F4-6CEB7CD7D73E Q52334786-16107F66-E1B4-41F2-97E2-2E6159992D60 Q52584711-AC6A195C-D273-4439-A7C8-EBCFB8141C05 Q52613750-9273E808-94DC-47A0-8634-624BFFB6F5D4 Q52624885-A38BDC6E-0AE5-4AB8-9D6A-48571905B2DB

P2860

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

http://www.wikidata.org/entity/Q38776637

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

@en

type

label

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

@en

prefLabel

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

@en

P1433

Q38776637-45F991B4-F4A0-44A3-A075-E9910BE63B17

P1476

Q38776637-42628564-46D7-4A6C-B5D9-57C42A417561

P2093

Q38776637-063D8CA7-A05E-410B-8E97-788FFB6984BC

Q38776637-323B38A1-053E-4499-BE6D-9E0581822F33

Q38776637-428E6C68-F335-4664-A3FC-668FD6310770

Q38776637-45BF11AA-C658-4873-8A54-0A2EC119F284

Q38776637-4E596624-4AF5-45D7-B260-2D46FA31D7B9

Q38776637-60A9097B-C206-4F18-B0E2-6A2C661C1459

Q38776637-7179AF2E-8A9B-491E-A68E-3A171D25A59E

Q38776637-7F111E9E-C1B0-4C0C-AE2E-8565BC8B988A

Q38776637-A3BE59AD-8520-404F-80DB-C8F424FE6AC3

Q38776637-A4C38644-0552-4494-A05E-06510079724A

P2860

Q38776637-01AB56F5-700E-4E43-9B02-FDD86928CE0C

Q38776637-0CA5EA33-0C65-42D2-BAF0-5C236D0C1716

Q38776637-105C2901-27E1-4690-B82A-F3D2C3EAE1A7

Q38776637-14C06287-937D-4745-BB7F-B83A486C6BC9

Q38776637-15AEF7EF-FAEC-4654-9F25-E2B9A90EC310

Q38776637-1BBB84BA-8EF2-493D-8DE3-70E0DFDAACB3

Q38776637-1DA5BD38-CB99-4F37-A8EB-C32FFC20288D

Q38776637-1DB2D068-5275-43DF-A2A0-A9832CFD4BE4

Q38776637-205FB523-0EC4-46A7-8646-2C8385D27C4C

Q38776637-24B3991D-4DAA-44F4-A729-7ECD8AF7CD39

P304

Q38776637-4A5D4412-62AF-4AC1-A50D-E42AC2293485

P31

Q38776637-CB692C5C-70D2-4879-9D99-5B53C0A8CC7F

P356

Q38776637-CEFEF444-4B84-4159-B280-15190BFABEFF

P433

Q38776637-351A6979-87C9-490E-A784-3EF84A14E6F9

P478

Q38776637-5F68359E-C295-4746-8782-992FC79690DD

P50

Q38776637-92007041-8616-40A8-A4C7-A3D60128AD79

Q38776637-D74D116E-00BB-4376-8184-C31913CAE4DA

P577

Q38776637-593EF634-0E73-4E22-9DC0-17BD7AD5E817

P698

Q38776637-B5A536F5-EB86-4300-BDFA-17D95EF99049

P932

Q38776637-0B49C6C7-EC3A-4070-BF08-A268D7930EBE

P356

2159-8290.CD-16-0217

P1433

Cancer Discovery

P1476

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

@en

P2093

Agustin Chicas

http://www.w3.org/2001/XMLSchema#string

Chi-Chao Chen

http://www.w3.org/2001/XMLSchema#string

Christopher R Vakoc

http://www.w3.org/2001/XMLSchema#string

Chun-Hao Huang

http://www.w3.org/2001/XMLSchema#string

Darjus F Tschaharganeh

http://www.w3.org/2001/XMLSchema#string

Jae-Seok Roe

http://www.w3.org/2001/XMLSchema#string

Jessica E Bolden

http://www.w3.org/2001/XMLSchema#string

Matthew Camiolo

http://www.w3.org/2001/XMLSchema#string

Myles Fennell

http://www.w3.org/2001/XMLSchema#string

Nilgun Tasdemir

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer

Senescence of activated stellate cells limits liver fibrosis

Histone H3K27ac separates active from poised enhancers and predicts developmental state

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

Suppression of inflammation by a synthetic histone mimic

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

P304

612-629

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/2159-8290.CD-16-0217

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Direna Alonso-Curbelo

P577

2016-04-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27099234

http://www.w3.org/2001/XMLSchema#string

P932

4893996

http://www.w3.org/2001/XMLSchema#string