Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.
about
SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC.SIRT6 deacetylates PKM2 to suppress its nuclear localization and oncogenic functions.SIRT6 Suppresses Pancreatic Cancer through Control of Lin28bInterplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity.Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells.SIRT6: Novel Mechanisms and Links to Aging and Disease.Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin.Mammalian target of rapamycin complex 2 (mTORC2) controls glycolytic gene expression by regulating Histone H3 Lysine 56 acetylation.An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality.
P2860
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P2860
Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Identification of and Molecula ...... ion Point Mutations in Cancer.
@en
type
label
Identification of and Molecula ...... ion Point Mutations in Cancer.
@en
prefLabel
Identification of and Molecula ...... ion Point Mutations in Cancer.
@en
P2093
P2860
P1433
P1476
Identification of and Molecula ...... ion Point Mutations in Cancer.
@en
P2093
Abbe R Clark
Carlos Sebastián
Dafne M Silberman
Jessica L Feldman
John M Denu
Mark A Klein
Raul Mostoslavsky
Sita Kugel
Stephanie Dobersch
P2860
P304
P356
10.1016/J.CELREP.2015.09.022
P577
2015-10-07T00:00:00Z