Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.
about
The actions of drug combinations on the GABAA receptor manifest as curvilinear isoboles of additivity.Anesthetic-Receptor Relationship Status: It's Complicated.Alphaxalone Binds in Inner Transmembrane β+-α- Interfaces of α1β3γ2 γ-Aminobutyric Acid Type A Receptors.Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics.General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type A Receptors (GABAARs).Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors.Recent progress on the molecular pharmacology of propofol.High constitutive activity accounts for the combination of enhanced direct activation and reduced potentiation in mutated GABAA receptors.Structural basis of neurosteroid anesthetic action on GABA receptors
P2860
Q38633275-636F8830-1BD1-42A4-84BA-4223BE903182Q45464094-5069BD0A-28AE-47A1-B571-C362F55BFE9BQ46287845-EAD68DA9-02A6-42E4-A718-12B1F3695F04Q47215880-C9170612-E7BB-420D-A4B9-4A966447FC0BQ47368001-A1D28537-3A89-4C8C-9C34-3D99B4506A04Q47388420-CED7AF96-7706-47EC-A967-233B6992CDD4Q49206852-FCD4C45D-4153-44C5-B021-AC1C15CB79A5Q50035831-9F8C9FEE-2CE0-4555-B3F5-8307787000A3Q59126131-7A443A49-1826-417A-9322-311957FA57CC
P2860
Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh-hant
name
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@en
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@nl
type
label
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@en
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@nl
prefLabel
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@en
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@nl
P2093
P2860
P1433
P1476
Tryptophan and Cysteine Mutati ...... esthetics and One Orphan Site.
@en
P2093
Alex T Stern
Anahita Nourmahnad
Andrea Szabo
Deirdre S Stewart
Mayo Hotta
Stuart A Forman
P2860
P304
P356
10.1097/ALN.0000000000001390
P407
P577
2016-10-07T00:00:00Z