Toxoplasma gondii Rhoptry Protein ROP16 Mediates Partially SH-SY5Y Cells Apoptosis and Cell Cycle Arrest by Directing Ser15/37 Phosphorylation of p53

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Functional Characterization of Rhoptry Kinome in the Virulent Toxoplasma gondii RH Strain.Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress.

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Toxoplasma gondii Rhoptry Protein ROP16 Mediates Partially SH-SY5Y Cells Apoptosis and Cell Cycle Arrest by Directing Ser15/37 Phosphorylation of p53

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Toxoplasma gondii Rhoptry Prot ...... er15/37 Phosphorylation of p53

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Toxoplasma gondii Rhoptry Prot ...... er15/37 Phosphorylation of p53

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Toxoplasma gondii Rhoptry Prot ...... er15/37 Phosphorylation of p53

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P1476

Toxoplasma gondii Rhoptry Prot ...... er15/37 Phosphorylation of p53

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P2093

Duan Ma

http://www.w3.org/2001/XMLSchema#string

Jin Zhang

http://www.w3.org/2001/XMLSchema#string

Nan Jiang

http://www.w3.org/2001/XMLSchema#string

Shuang Chang

http://www.w3.org/2001/XMLSchema#string

Steven Qian Zhang

http://www.w3.org/2001/XMLSchema#string

Weiwei Fan

http://www.w3.org/2001/XMLSchema#string

Xingliang Li

http://www.w3.org/2001/XMLSchema#string

Xiumei Shan

http://www.w3.org/2001/XMLSchema#string

Zuohua Mao

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P2860

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

Modes of p53 regulation

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.

Role of p53 serine 46 in p53 target gene regulation.

RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.

Modulation of innate immunity by Toxoplasma gondii virulence effectors.

Toxoplasma gondii clonal strains all inhibit STAT1 transcriptional activity but polymorphic effectors differentially modulate IFNγ induced gene expression and STAT1 phosphorylation

A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii.

Have it your way: how polymorphic, injected kinases and pseudokinases enable Toxoplasma to subvert host defenses.

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1215-1225

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scholarly article

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10.7150/IJBS.10516

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English

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2015-08-15T00:00:00Z

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281519183

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26327815

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Toxoplasma gondii

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4551757

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Toxoplasma gondii Rhoptry Protein ROP16 Mediates Partially SH-SY5Y Cells Apoptosis and Cell Cycle Arrest by Directing Ser15/37 Phosphorylation of p53

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P2860

P2860

Toxoplasma gondii Rhoptry Protein ROP16 Mediates Partially SH-SY5Y Cells Apoptosis and Cell Cycle Arrest by Directing Ser15/37 Phosphorylation of p53

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P356

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P2860

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P932