Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.
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The HTLV-1 Tax interactomeHighlights on distinctive structural and functional properties of HTLV Tax proteinsHuman T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human tax3 proteinRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityPresence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein.Genetic characterization of the complete genome of a highly divergent simian T-lymphotropic virus (STLV) type 3 from a wild Cercopithecus mona monkeyTax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Interaction of HTLV-1 Tax protein with calreticulin: implications for Tax nuclear export and secretion.Tus, an E. coli protein, contains mammalian nuclear targeting and exporting signalsAn RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation.Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformationGenotoxic stress and cellular stress alter the subcellular distribution of human T-cell leukemia virus type 1 tax through a CRM1-dependent mechanismRole of post-translational modifications of HTLV-1 Tax in NF-κB activation.Move or die: the fate of the Tax oncoprotein of HTLV-1.Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling.The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.Nuclear-to-cytoplasmic relocalization of the proliferating cell nuclear antigen (PCNA) during differentiation involves a chromosome region maintenance 1 (CRM1)-dependent export and is a prerequisite for PCNA antiapoptotic activity in mature neutrophHTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysUbiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.Dimerization and a novel Tax speckled structure localization signal are required for Tax nuclear localization.Role of resident CNS cell populations in HTLV-1-associated neuroinflammatory disease.HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replicationPresentation of human T cell leukemia virus type 1 (HTLV-1) Tax protein by dendritic cells: the underlying mechanism of HTLV-1-associated neuroinflammatory disease.HTLV gene regulation: because size matters, transcription is not enough.Stable ubiquitination of human T-cell leukemia virus type 1 tax is required for proteasome binding.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients.Human T-cell lymphotropic virus type 1 and its oncogenesis.Secretion of the human T cell leukemia virus type I transactivator protein tax.The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein.Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2.The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells.Functional analysis of human T lymphotropic virus type 2 Tax proteins.The tax protein from the primate T-cell lymphotropic virus type 3 is expressed in vivo and is functionally related to HTLV-1 Tax rather than HTLV-2 Tax.Regulation of NF-kappa B2 p100 processing by its cis-acting domain.A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution.
P2860
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P2860
Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Characterization of a nuclear ...... I transactivator protein Tax.
@en
type
label
Characterization of a nuclear ...... I transactivator protein Tax.
@en
prefLabel
Characterization of a nuclear ...... I transactivator protein Tax.
@en
P2093
P2860
P356
P1476
Characterization of a nuclear ...... I transactivator protein Tax.
@en
P2093
Brian Wigdahl
Christian Grant
Edward W Harhaj
Kate Barmak
Timothy Alefantis
P2860
P304
21814-21822
P356
10.1074/JBC.M211576200
P407
P577
2003-04-01T00:00:00Z