Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. - Wikidata - awgldk - TriplyDB

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

http://www.wikidata.org/entity/Q38923789

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A microRNA signature for a BMP2-induced osteoblast lineage commitment program Potential mechanisms underlying the Runx2 induced osteogenesis of bone marrow mesenchymal stem cells A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation Regulation of gene expression in osteoblasts.MicroRNAs regulate bone development and regeneration Prospects for osteoprogenitor stem cells in fracture repair and osteoporosis F-spondin deficient mice have a high bone mass phenotype.Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.Novel links among Wnt and TGF-beta signaling and Runx2.Melanin extract from Gallus gallus domesticus promotes proliferation and differentiation of osteoblastic MG-63 cells via bone morphogenetic protein-2 signaling.A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis Runt-related transcription factors impair activin induction of the follicle-stimulating hormone {beta}-subunit gene.The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts Genetic and transcriptional control of bone formation The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.Metastatic bone disease: role of transcription factors and future targets.Calcium-mediated stress kinase activation by DMP1 promotes osteoblast differentiation.Immortalized mouse floxed Bmp2 dental papilla mesenchymal cell lines preserve odontoblastic phenotype and respond to BMP2.The Role of RUNX2 in Osteosarcoma Oncogenesis.Development and characterization of a mouse floxed Bmp2 osteoblast cell line that retains osteoblast genotype and phenotype.Integration of multiple signaling regulates through apoptosis the differential osteogenic potential of neural crest-derived and mesoderm-derived Osteoblasts Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.Runx2-Smad signaling impacts the progression of tumor-induced bone disease 1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA Nell-1, a key functional mediator of Runx2, partially rescues calvarial defects in Runx2(+/-) mice.Age-dependent alteration of TGF-β signalling in osteoarthritis.Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency.Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1 Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation.Orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) protein negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation through suppressing runt-related gene 2 (Runx2) activity.Do epigenetic marks govern bone mass and homeostasis?Signaling networks that control the lineage commitment and differentiation of bone cells.Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells Bioreactors to influence stem cell fate: augmentation of mesenchymal stem cell signaling pathways via dynamic culture systems.Enhancement of osteogenic differentiation of rat adipose tissue-derived mesenchymal stem cells by zinc sulphate under electromagnetic field via the PKA, ERK1/2 and Wnt/β-catenin signaling pathways.MicroRNA control of bone formation and homeostasis.Establishment of Immortalized BMP2/4 Double Knock-Out Osteoblastic Cells Is Essential for Study of Osteoblast Growth, Differentiation, and Osteogenesis Integration of multiple signaling pathways determines differences in the osteogenic potential and tissue regeneration of neural crest-derived and mesoderm-derived calvarial bones Biglycan induces the expression of osteogenic factors in human aortic valve interstitial cells via Toll-like receptor-2.

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Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

http://www.wikidata.org/entity/Q38923789

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

@en

type

label

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

@en

prefLabel

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

@en

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Journal of Biological Chemistry

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Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal

@en

P2093

Andre J van Wijnen

http://www.w3.org/2001/XMLSchema#string

Faiza Afzal

http://www.w3.org/2001/XMLSchema#string

Gary S Stein

http://www.w3.org/2001/XMLSchema#string

Jane B Lian

http://www.w3.org/2001/XMLSchema#string

Janet L Stein

http://www.w3.org/2001/XMLSchema#string

Jitesh Pratap

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Jong-Sup Bae

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Soraya Gutierrez

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Yang Lou

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P2860

Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

Mutations in the RUNX2 gene in patients with cleidocranial dysplasia

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

Runx2: a master organizer of gene transcription in developing and maturing osteoblasts

Smad transcription factors

SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation

BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression

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8412-8422

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scholarly article

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10.1074/JBC.M705578200

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P433

13

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283

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Sayyed K. Zaidi

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2008-01-18T00:00:00Z

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18204048

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2417186

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