Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives.
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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules.Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors.3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.Division of labor among Mycobacterium smegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase.Chelation Motifs Affecting Metal-dependent Viral Enzymes: N'-acylhydrazone Ligands as Dual Target Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H DomainTherapeutic potentials of short interfering RNAs.Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding.Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase.Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities.Biological Activities of Aerial Parts Extracts of Euphorbia characias.From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors.Enzymatic Activities of RNase H Domains of HIV-1 Reverse Transcriptase with Substrate Binding Domains of Bacterial RNases H1 and H2.Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.Uvaria angolensis as a promising source of inhibitors of HIV-1 RT-associated RNA-dependent DNA polymerase and RNase H functions.Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studiesFrom cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitorsRecent advances in the discovery of small-molecule inhibitors of HIV-1 integrase
P2860
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P2860
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-my
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name
Identification of highly conse ...... on by Diketo acid derivatives.
@en
type
label
Identification of highly conse ...... on by Diketo acid derivatives.
@en
prefLabel
Identification of highly conse ...... on by Diketo acid derivatives.
@en
P2093
P2860
P50
P356
P1476
Identification of highly conse ...... on by Diketo acid derivatives.
@en
P2093
Frederic Subra
Giuliana Cuzzucoli Crucitti
Giuseppe Rigogliuso
Luca Pescatori
Olivier Delelis
Sylvain Thierry
P2860
P304
P356
10.1128/AAC.03605-14
P407
P50
P577
2014-08-04T00:00:00Z