Design of new α-conotoxins: from computer modeling to synthesis of potent cholinergic compounds.
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Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRsMarine natural products acting on the acetylcholine-binding protein and nicotinic receptors: from computer modeling to binding studies and electrophysiology.αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR.High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method.Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides.Natural compounds interacting with nicotinic acetylcholine receptors: from low-molecular weight ones to peptides and proteins.α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition.Computational exploration of a protein receptor binding space with student proposed peptide ligands.Azemiopsin, a Selective Peptide Antagonist of Muscle Nicotinic Acetylcholine Receptor: Preclinical Evaluation as a Local Muscle Relaxant.
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P2860
Design of new α-conotoxins: from computer modeling to synthesis of potent cholinergic compounds.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Design of new α-conotoxins: fr ...... potent cholinergic compounds.
@en
type
label
Design of new α-conotoxins: fr ...... potent cholinergic compounds.
@en
prefLabel
Design of new α-conotoxins: fr ...... potent cholinergic compounds.
@en
P2093
P2860
P356
P1433
P1476
Design of new α-conotoxins: fr ...... potent cholinergic compounds.
@en
P2093
Alexey Y Khruschov
Igor E Kasheverov
Maxim N Zhmak
Victor I Tsetlin
P2860
P304
P356
10.3390/MD9101698
P577
2011-09-28T00:00:00Z