Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection.
about
Role of Deubiquitinating Enzymes in DNA RepairProlyl isomerase Pin1 in cancerPhosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme.Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMOCullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resectionA fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.The Ess1 prolyl isomerase: traffic cop of the RNA polymerase II transcription cycle.The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.Prolyl isomerases in gene transcriptionWee1 is required to sustain ATR/Chk1 signaling upon replicative stress.Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand break repairA genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice.Controlling DNA-end resection: a new task for CDKs.Sharpening the ends for repair: mechanisms and regulation of DNA resection.Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin.Prognostic value of CtIP/RBBP8 expression in breast cancer.ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair.CtIP/Ctp1/Sae2, molecular form fit for function.ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1.The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.The role of Pin1 in the development and treatment of cancer.miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP.Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resectionThe control of DNA repair by the cell cycle.Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA.AUNIP/C1orf135 directs DNA double-strand breaks towards the homologous recombination repair pathway.Prolyl isomerization: a new PIN code for DSB repair.Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks.Prolyl isomerase Pin1: a promoter of cancer and a target for therapyGears-In-Motion: The Interplay of WW and PPIase Domains in Pin1
P2860
Q26773800-4D032B92-199E-40C6-AAF3-6A1D3BEF4ADAQ27024695-301364EB-B527-41FD-B1CD-18ACEB897A0CQ27936967-BAACBE09-8FDC-4AB6-BD69-6D6BAE95377CQ28069597-DFF29734-6C95-4AD4-8C45-F0CC5B5BB989Q28118714-6512CC38-E139-45BB-AA1E-CF26F9EA04DAQ33698648-2D770730-AFBD-40CA-9FCB-A75E937B935DQ33726010-F27D8702-23FB-4156-BBA7-F56D12A509FDQ34249598-048C361A-BB7A-4AC5-AC60-6C20D3281A61Q34806918-EA53F6B6-B248-440E-A2B7-131F0A100219Q35561852-F2CDEFE5-8018-4E94-A775-6676B6721E71Q35955216-78906EE7-7611-44C5-B24E-964FBD97E849Q36002411-7278D3B8-3831-4B43-B2B0-5FBB1F0CC02BQ36098301-8ADF2C4A-2553-4611-89ED-85B03FB69EA2Q36854994-C61078DA-3B9F-4E8F-B8B7-BC7266A68D45Q36893881-623213CD-677D-42B8-9F6F-F4100DC0E5C9Q37058602-247AAA54-1005-4BF2-8D47-4D143123D575Q37233602-F085A241-388C-40C0-9381-6A8D9A677675Q37481139-F3B14C48-AA1A-4640-A111-3EF3072639E1Q38225143-18219FB3-BA59-4E9E-B6E8-28619BB46F3EQ38721827-50412559-050A-49B8-9327-32EEB33A1C07Q38834012-9C414E3A-8412-46C0-B725-FF8598648913Q38852028-4B1A4FE0-C496-49C8-862A-EDEA68D87C77Q38939954-040893EC-DE83-49B9-B86F-DF5F6830B845Q38948631-AD995FB9-D542-455C-81F6-5599013E08F6Q38994140-62F47A63-B6E6-4669-83CE-7720388404DFQ39051119-7BDD8CAF-8FE9-4EC6-9532-C8AADAFF1EC1Q42200149-B6D72498-A863-4E1D-AA06-6E2285C794FDQ42379646-32F4F4EF-D55D-4E5E-A3AC-61D0902DB29BQ42736615-E3C6970C-162E-4D36-AF42-205B66579F01Q55511176-0E6C724C-AF47-4963-9DDB-0AF4707ACF67Q58695611-FACA9C1B-7493-4951-BF21-08662A358F7EQ59127766-FF044197-7EAD-4C97-BC22-B252EB584DE7
P2860
Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@en
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@nl
type
label
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@en
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@nl
prefLabel
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@en
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@nl
P2093
P50
P1433
P1476
Prolyl isomerase PIN1 regulate ...... unteracting DNA end resection.
@en
P2093
Bertran Gerrits
Christine Neugebauer
Daniela Hühn
Lorenza P Ferretti
Lorenzo Lafranchi
Martin Steger
Oliver Zerbe
Pavel Janscak
Reto Walser
Shreya Paliwal
P304
P356
10.1016/J.MOLCEL.2013.03.023
P577
2013-04-25T00:00:00Z