Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties.

Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties.

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http://www.wikidata.org/entity/Q39168354
Design of small molecule epigenetic modulatorsKDM1 class flavin-dependent protein lysine demethylasesThe Enantioselective Dakin-West Reaction.Identification of Novel Selective Lysine-Specific Demethylase 1 (LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking.Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date.Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.The chemistry and biology of guanidine natural products.Inhibitors of Protein Methyltransferases and Demethylases.Insight into the binding mode of a novel LSD1 inhibitor by molecular docking and molecular dynamics simulations.Histone Lysine Demethylase Inhibitors.Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases.A selective phenelzine analogue inhibitor of histone demethylase LSD1.A Pd-based regioselective strategy to indole-1,2-fused 8- and 9-membered rings: their evaluation as potential scaffolds for apoptosis in zebrafish.The Enantioselective Dakin-West Reaction
P2860

Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties.

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http://www.wikidata.org/entity/Q39168354
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Synthesis and evaluation of 3- ...... anti-proliferative properties.
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Synthesis and evaluation of 3- ...... anti-proliferative properties.
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type
label
Synthesis and evaluation of 3- ...... anti-proliferative properties.
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Synthesis and evaluation of 3- ...... anti-proliferative properties.
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prefLabel
Synthesis and evaluation of 3- ...... anti-proliferative properties.
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Synthesis and evaluation of 3- ...... anti-proliferative properties.
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Synthesis and evaluation of 3- ...... anti-proliferative properties.
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P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698