A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies. - Wikidata - awgldk - TriplyDB

A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies.

A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies.

http://www.wikidata.org/entity/Q39297135

about

Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei When lamins go bad: nuclear structure and disease The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse Multiparameter mechanical and morphometric screening of cells.Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.DNA damage and lamins Deletion of the lmna gene induces growth delay and serum biochemical changes in C57BL/6 mice Nuclear lamins and neurobiology.An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin Accessorizing and anchoring the LINC complex for multifunctionality.Lamins in development, tissue maintenance and stress.Lamin A/C is expressed in pluripotent mouse embryonic stem cells.Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling.Targeting Mitogen-Activated Protein Kinase Signaling in Mouse Models of Cardiomyopathy Caused by Lamin A/C Gene Mutations Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells.Generation and characterization of a conditional deletion allele for Lmna in mice.Developmental regulation of linkers of the nucleoskeleton to the cytoskeleton during mouse postnatal retinogenesis.Broken nuclei--lamins, nuclear mechanics, and disease.Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease.Role of nuclear Lamin A/C in cardiomyocyte functions.Lamin A/C sustains PcG protein architecture, maintaining transcriptional repression at target genes.Mechanosensing by the nucleus: From pathways to scaling relationships.Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability.Overview of the Muscle Cytoskeleton.Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects.Recruitment of HP1β to UVA-induced DNA lesions is independent of radiation-induced changes in A-type lamins.Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.Mechanotransduction, nuclear architecture and epigenetics in Emery Dreifuss Muscular Dystrophy: tous pour un, un pour tous.SMAD6 overexpression leads to accelerated myogenic differentiation of LMNA mutated cells.Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins.Linker of nucleoskeleton and cytoskeleton complex proteins in cardiomyopathy Exploring the Crosstalk Between and Splicing Machinery Gene Mutations in Dilated Cardiomyopathy The Pathogenesis and Therapies of Striated Muscle Laminopathies Genetic mutation of familial dilated cardiomyopathy based on next‑generation semiconductor sequencing

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A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies.

http://www.wikidata.org/entity/Q39297135

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

@en

A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

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type

label

A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

@en

A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

@nl

prefLabel

A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

@en

A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

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A truncated lamin A in the Lmn ...... nderstanding of laminopathies.

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Chris G de Koster

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Clemens J Heilmann

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Daniel Jahn

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Manfred Alsheimer

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Ricardo Benavente

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Sabine Schramm

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Wolfgang Schütz

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P2860

Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

Coupling of the nucleus and cytoplasm: role of the LINC complex

Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C

Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes

Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope

Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics.

Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse

Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases

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10.4161/NUCL.21676

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5

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3

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Martina Schnölzer

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2012-08-16T00:00:00Z

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230677989

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