Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist.
about
Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulationSolomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons.Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei.
P2860
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist.
description
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name
Modification in the side chain ...... t pregnane-X-receptor agonist.
@en
Modification in the side chain ...... t pregnane-X-receptor agonist.
@nl
type
label
Modification in the side chain ...... t pregnane-X-receptor agonist.
@en
Modification in the side chain ...... t pregnane-X-receptor agonist.
@nl
prefLabel
Modification in the side chain ...... t pregnane-X-receptor agonist.
@en
Modification in the side chain ...... t pregnane-X-receptor agonist.
@nl
P2093
P2860
P50
P356
P1476
Modification in the side chain ...... nt pregnane-X-receptor agonist
@en
P2093
Barbara Renga
Gianluigi Lauro
Maria Valeria D'Auria
Raffaella Ummarino
Stefano Fiorucci
Valentina Sepe
P2860
P304
P356
10.1039/C2OB25800E
P577
2012-06-26T00:00:00Z