Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.
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The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in NeurodegenerationProtein disulfide isomerases in neurodegeneration: from disease mechanisms to biomedical applicationsOxidative stress and mitochondrial damage: importance in non-SOD1 ALSRedox regulation in amyotrophic lateral sclerosisALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationA novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumEndoplasmic reticulum stress and inflammation in the central nervous systemProtein disulfide isomerase interacts with tau protein and inhibits its fibrillization.Novel roles for protein disulphide isomerase in disease states: a double edged sword?Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences.Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats.Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders.ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1Protein Quality Control by Molecular Chaperones in Neurodegeneration.Protein aggregation in amyotrophic lateral sclerosis.Advances in cellular models to explore the pathophysiology of amyotrophic lateral sclerosis.ER Dysfunction and Protein Folding Stress in ALS.The role of s-nitrosylation and s-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration.Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.Increased expression of microRNA-29a in ALS mice: functional analysis of its inhibition.S-nitrosylation of the thioredoxin-like domains of protein disulfide isomerase and its role in neurodegenerative conditions.Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.The redox switch that regulates molecular chaperones.ER stress and the unfolded protein response in neurodegeneration.Old versus New Mechanisms in the Pathogenesis of ALS.The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.Protein Disulphide Isomerases: emerging roles of PDI and ERp57 in the nervous system and as therapeutic targets for ALS.Cysteine Modifications in the Pathogenesis of ALS.Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic SignificanceFine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis.ALS-linked protein disulfide isomerase variants cause motor dysfunction.ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.Identification of rare protein disulfide isomerase gene variants in amyotrophic lateral sclerosis patients.Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand.Proteostasis disturbance in amyotrophic lateral sclerosis.Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.
P2860
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P2860
Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Mutant FUS induces endoplasmic ...... h protein disulfide-isomerase.
@en
Mutant FUS induces endoplasmic ...... h protein disulfide-isomerase.
@nl
type
label
Mutant FUS induces endoplasmic ...... h protein disulfide-isomerase.
@en
Mutant FUS induces endoplasmic ...... h protein disulfide-isomerase.
@nl
prefLabel
Mutant FUS induces endoplasmic ...... h protein disulfide-isomerase.
@en
Mutant FUS induces endoplasmic ...... h protein disulfide-isomerase.
@nl
P2093
P50
P1476
Mutant FUS induces endoplasmic ...... th protein disulfide-isomerase
@en
P2093
Jacqueline Orian
Malcolm K Horne
Manal A Farg
Sadaf T Warraich
P304
P356
10.1016/J.NEUROBIOLAGING.2012.02.009
P577
2012-03-28T00:00:00Z