Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.
about
Revisiting voltage-dependent relief of block in ion channels: a mechanism independent of punchthrough.Cystic fibrosis transmembrane conductance regulator chloride channel blockers: Pharmacological, biophysical and physiological relevance.Anion currents in yeast K+ transporters (TRK) characterize a structural homologue of ligand-gated ion channels.Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane.Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel.Insight in eukaryotic ABC transporter function by mutation analysis.Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore.Tuning of CFTR chloride channel function by location of positive charges within the pore.Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore.Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function.Regulation of CFTR chloride channel macroscopic conductance by extracellular bicarbonate.Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel.Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate.State-dependent access of anions to the cystic fibrosis transmembrane conductance regulator chloride channel pore.On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore.Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS.Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Positive charges at the intracellular mouth of the pore regulate anion conduction in the CFTR chloride channel.Evidence that extracellular anions interact with a site outside the CFTR chloride channel pore to modify channel properties.Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel.Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.
P2860
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P2860
Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@en
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@nl
type
label
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@en
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@nl
prefLabel
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@en
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@nl
P2860
P356
P1476
Mutation-induced blocker perme ...... he CFTR chloride channel pore.
@en
P2093
Xiandi Gong
P2860
P304
P356
10.1085/JGP.200308889
P577
2003-11-10T00:00:00Z